Alexander A. Aksenov
University of Montana
126 Papers
239 Citations
Alexander A. Aksenov is an academic researcher from University of Montana. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 26, co-authored 85 publications. Previous affiliations of Alexander A. Aksenov include University of Florida & Carnegie Mellon University.
Chat about Author
Papers
Interleukin-17 Inhibition in Spondyloarthritis Is Associated With Subclinical Gut Microbiome Perturbations and a Distinctive Interleukin-25-Driven Intestinal Inflammation.
Julia Manasson,David S. Wallach,Giuliana Guggino,Matthew Stapylton,Michelle H. Badri,Gary Solomon,Soumya M. Reddy,Roxana Coras,Alexander A. Aksenov,Drew R. Jones,Parvathy V. Girija,Andrea L. Neimann,Adriana Heguy,Leopoldo N. Segal,Pieter C. Dorrestein,Richard Bonneau,Monica Guma,Francesco Ciccia,Carles Ubeda,Jose C. Clemente,Jose U. Scher +20 more
TL;DR: The ecological effects of biologic therapies on the gut bacterial and fungal microbiome in psoriatic arthritis (PsA)/spondyloarthritis (SpA) patients are characterized.
60
CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM).
Anjan Debnath,Claudia M. Calvet,Claudia M. Calvet,Gareth K. Jennings,Wenxu Zhou,Alexander A. Aksenov,Madeline R. Luth,Ruben Abagyan,W. David Nes,James H. McKerrow,Larissa M. Podust +10 more
TL;DR: The impact of anti-fungal azole drugs, known as conazoles, on sterol biosynthesis and viability of cultured N. fowleri trophozotes and target-based and parasite-based data obtained in these studies validated CYP51 as a potentially ‘druggable’ target in N.fowleri, and conazole drugs as the candidates for assessment in the animal model of PAM.
An Easy to Manufacture Micro Gas Preconcentrator for Chemical Sensing Applications
Mitchell M. McCartney,Yuriy Zrodnikov,Alexander G. Fung,Michael K. LeVasseur,Josephine M. Pedersen,Konstantin O. Zamuruyev,Alexander A. Aksenov,Nicholas J. Kenyon,Cristina E. Davis +8 more
TL;DR: A simple-to-manufacture microfabricated gas preconcentrator for MEMS-based chemical sensing applications that was capable of measuring analytes down to 22 ppb with only a 2 min sample loading time using a gas chromatograph with a flame ionization detector.
Synthetic blends of volatile, phytopathogen-induced odorants can be used to manipulate vector behavior
TL;DR: An equimolar mixture of compounds mimicking the volatile profile of HLB-infected citrus bound chemosensory proteins resulted in development of a synthetic lure that was more attractive to D. citri than natural citrus tree volatiles.
Determination of iron content and dispersity of intact ferritin by superconducting tunnel junction cryodetection mass spectrometry.
TL;DR: The structural integrity of HS-HoloFt and the proposed mineral adducts found for both purified L and H subunits suggest a robust biomacromolecular complex that is internally stabilized by the iron-based core.
30