Aleksandra Zivkovic
University of Düsseldorf
44 Papers
361 Citations
Aleksandra Zivkovic is an academic researcher from University of Düsseldorf. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 15, co-authored 33 publications. Previous affiliations of Aleksandra Zivkovic include Goethe University Frankfurt.
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Papers
Synthesis of modified RNA-oligonucleotides for structural investigations
TL;DR: Different fluoromodifications of RNA building blocks were synthesized and amidites were incorporated and tested in a defined A, U- rich RNA sequence (12-mer, 5′-CUU UUC XUU CUU-3′ paired with 3′-GAA AAG YAA GAA-5’)
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Synthesis, in silico, and in vitro studies of novel dopamine D 2 and D 3 receptor ligands
Milica Elek,Nemanja Djokovic,Annika Frank,Slavica Oljačić,Aleksandra Zivkovic,Katarina Nikolic,Holger Stark +6 more
TL;DR: In this paper, the binding of novel compounds at the dopamine D2 (D2 R) and D3 (D3 R) receptor subtypes, which belong to the D2 -like receptor family, was studied.
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BOPPY-based novel fluorescent dopamine D2 and D3 receptor ligands.
TL;DR: In this article , the authors used BOPPY labeling of D2R/D3R pharmacophores to obtain ligands with moderate to low nanomolar binding affinities as well as low to excellent quantum yields for bright fluorescence ligands.
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RNA recognition by fluor-aromatic substituted.
TL;DR: Different fluoromodifications of RNA building blocks were synthesized and amidites were incorporated and tested in a defined A, U-rich RNA sequence and UV melting profiles of those oligonucleotides were measured.
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Histamine H3 receptor antagonists with peptidomimetic (keto)piperazine structures to inhibit Aβ oligomerisation.
Markus Falkenstein,David Reiner-Link,Aleksandra Zivkovic,Ian Gering,Dieter Willbold,Dieter Willbold,Holger Stark +6 more
TL;DR: In this paper, the design of disease modifying multi target directed ligand (MTDL) has been performed, which disable PPI on the one hand and on the other hand act as procognitive antagonists at the histamine H3 receptor (H3R).
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