Alek Erickson
University of Nebraska Medical Center
15 Papers
3 Citations
Alek Erickson is an academic researcher from University of Nebraska Medical Center. The author has contributed to research in topics: Biology & Neural crest. The author has an hindex of 5, co-authored 7 publications. Previous affiliations of Alek Erickson include Karolinska Institutet.
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Papers
Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.
Polina Kameneva,Artem V. Artemov,Maria Eleni Kastriti,Maria Eleni Kastriti,Louis Faure,Thale Kristin Olsen,Jörg Otte,Alek Erickson,Bettina Semsch,Emma Andersson,Michael Ratz,Jonas Frisén,Arthur S. Tischler,Ronald R. de Krijger,Thibault Bouderlique,Natalia Akkuratova,Natalia Akkuratova,Maria Vorontsova,Maria Vorontsova,Oleg Gusev,Kaj Fried,Erik Sundström,Shenglin Mei,Per Kogner,Ninib Baryawno,Peter V. Kharchenko,Igor Adameyko,Igor Adameyko +27 more
TL;DR: This article examined the transcriptional states of neural crest-and mesoderm-derived lineages differentiating into adrenal glands, kidneys, endothelium and hematopoietic tissue between post-conception weeks 6 and 14 of human development.
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Schwann cell precursors represent a neural crest‐like state with biased multipotency
Maria Eleni Kastriti,Louis Faure,Dorothea Von Ahsen,Thibault Bouderlique,Johan Boström,Tatiana Solovieva,Cameron B. Jackson,Marianne E. Bronner,Dies Meijer,Saida Hadjab,Francois Lallemend,Alek Erickson,Marketa Kaucka,Viacheslav Dyachuk,Thomas Perlmann,Laura Lahti,Jan Krivanek,Jean-François Brunet,Kaj Fried,Igor Adameyko +19 more
TL;DR: Overall, SCPs resemble migrating neural crest cells that maintain multipotency and become transcriptionally primed towards distinct lineages.
61
Mechanical stimulation of growth plate chondrocytes: Previous approaches and future directions.
TL;DR: It is explored how microfluidics devices can overcome limitations and improve current understanding of growth plate chondrocyte mechanobiology and enable real-time monitoring of metabolism and cellular behavior using optical microscopy.
26
The transcriptional portraits of the neural crest at the individual cell level
TL;DR: In this article , a marriage between single cell multi-omics, statistical modeling, and developmental biology has shed a substantial amount of light on these questions, and has paved a clear path for future researchers in the field.
21
A branching model of cell fate decisions in the enteric nervous system
Anna Laddach,Song Hui Chng,Reena Lasrado,Fränze Progatzky,Michael Shapiro,Artem V. Artemov,Marisol Sampedro Castañeda,Alek Erickson,Ana Carina Bon-Frauches,Jens Kleinjung,Stefan Boeing,Sila K. Ultanir,Igor Adameyko,Vassilis Pachnis +13 more
TL;DR: The studies uncover a novel configuration ofEnteric neurogenesis and gliogenesis that enables the coordinate development of ENS lineages and provides a mechanistic explanation for the ability of enteric glia to be functionally integrated into the adult intestine and simultaneously maintain attributes of early ENS progenitors.