Albert E. Munson
National Institute for Occupational Safety and Health
19 Papers
180 Citations
Albert E. Munson is an academic researcher from National Institute for Occupational Safety and Health. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 11, co-authored 19 publications. Previous affiliations of Albert E. Munson include VCU Medical Center.
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Papers
Evaluation of the Contact and Respiratory Sensitization Potential of Volatile Organic Compounds Generated by Simulated Indoor Air Chemistry
Stacey E. Anderson,J. R. Wells,Adam Fedorowicz,Leon Butterworth,B. J. Meade,Albert E. Munson +5 more
TL;DR: The four compounds generated by indoor air chemistry were predicted by QSAR and animal modeling to be sensitizers, with the potential for methylglyoxal to induce IgE.
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Mitochondrial dysfunction and loss of Parkinson's disease-linked proteins contribute to neurotoxicity of manganese-containing welding fumes
Krishnan Sriram,Gary X. Lin,Amy M. Jefferson,Jenny R. Roberts,Oliver Wirth,Yusuke Hayashi,Kristine Krajnak,Joleen M. Soukup,Andrew J. Ghio,Steven H. Reynolds,Vincent Castranova,Albert E. Munson,James M. Antonini +12 more
TL;DR: This work investigated the association of PD-linked (Park) genes and mitochondrial function in causing dopaminergic abnormality in rats exposed to manual metal arc-hard surfacing fumes and found altered expression of Parkin, Uchl1, and Dj1 proteins in dopamine brain areas.
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Comparison of mouse strains using the local lymph node assay
TL;DR: DBA/2, B6C3F1 and BALB/c mice are good choices for continued evaluation as additional mouse strains for use in the LLNA based on these studies.
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Immunological evaluation of the mycotoxin patulin in female B6C3F1 mice.
G.C Llewellyn,J. A. Mccay,Brown Rd,D. L. Musgrove,Leon F. Butterworth,Albert E. Munson,Kimber L. White +6 more
TL;DR: Oral exposure to patulin for 28 days did not alter the ability of female B6C3F1 mice to mount either a cell-mediated or humoral immune response, and Humoral immune function as assessed by antibody-forming cell response and serum IgM titre to sheep erythrocytes, and cell- mediated immune function evaluated utilizing natural killer cell activity and the mixed lymphocyte reaction were not altered.
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Assessment of the functional integrity of the humoral immune response: the plaque-forming cell assay and the enzyme-linked immunosorbent assay.
TL;DR: It has been suggested that the primary antibody response to sRBCs, as measured by an ELISA, may also be evaluated in the main group of animals in a toxicology study without compromise to the integrity of other toxicological endpoints.
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