A system of devices for treating an artery includes an arterial access sheath adapted to introduce an interventional catheter into an artery and an elongated dilator positionable within the internal lumen of the sheath body. The system also includes a catheter formed of an elongated catheter body sized and shaped to be introduced via a carotid artery access site into a common carotid artery through the internal lumen of the arterial access sheath. The catheter has an overall length and a distal most section length such that the distal most section can be positioned in an intracranial artery and at least a portion of the proximal most section is positioned in the common carotid artery during use.

Methods and systems for treatment of acute ischemic stroke

A method is provided, including implanting at least a first tissue-engaging element (60a) in a first portion of tissue in a vicinity of a heart valve (4) of a patient, implanting at least a second tissue-engaging element (60b) in a portion of a blood vessel (8, 10) that is in contact with an atrium (6) of a heart (2) of the patient, and drawing at least a first leaflet of the valve (4) toward at least a second leaflet of the valve (4) by adjusting a distance between the portion of the blood vessel (8, 10) and the first portion of tissue in the vicinity of the heart valve (4) of the patient. Other applications are also described.

Tricuspid valve repair using tension

Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.

Methods and systems for establishing retrograde carotid arterial blood flow

A cannula assembly, further comprising a cannula body for directing blood from the heart of a patient, having distal and proximal ends and a lumen therebetween. A tip coupled to the distal end of the body, the tip having an opening. A pump for drawing blood into the cannula assembly and dispensing the blood from the cannula assembly and into the patient circulatory system. The lumen of the cannula body further comprises a first inner diameter at the proximal end and a second inner diameter at the distal end, the first inner diameter being larger than the second inner diameter. A tapered portion defined as a decrease in inner diameter from the first inner diameter to the second inner diameter between the proximal and distal ends, the tapered portion configured to prevent cavitation of the blood within the cannula.

Transseptal cannula, tip, delivery system, and method

Apparatus is provided including a first tissue-engaging element (60a), a first flexible longitudinal member (2612) coupled at a first end portion (2613) thereof to at least a portion of the first tissue-engaging element (60a), and a first flexible-longitudinal-member-coupling element (2614) coupled to the first flexible longitudinal member (2612) at a second end portion (2615) of the first flexible longitudinal member (2612). Apparatus includes a second tissue-engaging element (60b), a second flexible longitudinal member (2660) coupled at a first end portion thereof to at least a portion of the second tissue-engaging element (60b), and a second flexible-longitudinal-member-coupling element (2650) coupled to the second flexible longitudinal member (2660) at a second end portion (2662) of the second flexible longitudinal member (2660), the first and second flexible-longitudinal-member-coupling elements (2614, 2650) being couplable to couple together the first and second flexible longitudinal elements (2612, 2660). Other applications are also described.

Method and apparatus for tricuspid valve repair using tension

Systems and methods are adapted for treating the carotid artery. The systems include interventional catheters and blood vessel access devices that are adapted for transcervical insertion into the carotid artery. Embodiments of the systems and methods can be used in combination with embolic protection systems including blood flow reversal mechanisms, arterial filters, and arterial occlusion devices.

Systems And Methods For Treating A Carotid Artery

A suture-based vessel closure device can perform the dilation of an arteriotomy puncture and does not require previous dilation of the arteriotomy puncture by a separate device or by a procedural sheath dilator. The suture-based vessel closure device can place one or more sutures across the vessel access site such that, when the suture ends are tied off after sheath removal, the stitch or stitches provide hemostasis to the access site.

Suture delivery device

An interventional catheter is adapted for treating a blood vessel. In an embodiment, the catheter includes an elongate shaft sized for insertion in a blood vessel and a stent positioned on a distal region of the elongate shaft. An expandable dilation member is coupled to a distal region of the elongate shaft. The expandable dilation member is adapted to expand outward. A stent containment member is positioned over the elongate shaft and the stent to contain the stent in a collapsed state.

Interventional catheter system and methods

A clip-based vascular closure devices is configured to be pre-applied to a blood vessel prior to insertion of a vascular access device (such as a procedural sheath) through an incision, puncture, penetration or other passage through the blood vessel. In an embodiment, the disclosed closure device is applied in a carotid artery via a transcervical access such as by forming an incision in the patient's neck to in order to access the blood vessel or other body lumen.

Vessel closure clip device

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