Alain Fischer
University of Paris
805 Papers
7.3K Citations
Alain Fischer is an academic researcher from University of Paris. The author has contributed to research in topics: Transplantation & Medicine. The author has an hindex of 143, co-authored 770 publications. Previous affiliations of Alain Fischer include French Institute of Health and Medical Research & Boston Children's Hospital.
Chat about Author
Papers
Current Spectrum of Infections in Patients with X-Linked Agammaglobulinemia.
Olivier Paccoud,Nizar Mahlaoui,Despina Moshous,Claire Aguilar,Bénédicte Neven,Fanny Lanternier,Felipe Suarez,Capucine Picard,Alain Fischer,Stéphane Blanche,Marc Lecuit,Marc Lecuit,Olivier Hermine,Olivier Lortholary +13 more
TL;DR: In this paper, the authors carried out a retrospective cross-sectional analysis of the records of X-linked agammaglobulinemia (XLA) patients seen at Necker-Enfants Malades Hospital, Paris.
11
Tetratricopeptide repeat domain 7A is a nuclear factor that modulates transcription and chromatin structure
Marie-Thérèse El-Daher,Marie-Thérèse El-Daher,Nicolas Cagnard,Nicolas Cagnard,Marine Gil,Marie Chansel Da Cruz,Marie Chansel Da Cruz,Claire Leveau,Claire Leveau,Fernando E. Sepulveda,Fernando E. Sepulveda,Mohammed Zarhrate,Frédéric Tores,Patricia Legoix,Sylvain Baulande,Jean-Pierre de Villartay,Jean-Pierre de Villartay,Geneviève Almouzni,Geneviève Almouzni,Jean-Pierre Quivy,Jean-Pierre Quivy,Alain Fischer,Geneviève de Saint Basile,Geneviève de Saint Basile,Geneviève de Saint Basile +24 more
TL;DR: Observations characterize for the first time unreported functions for TTC7A in the nucleus that exert a critical role in chromatin organization and gene regulation to safeguard healthy immune and intestinal status.
Opposing effects of protein tyrosine kinase inhibitors on the monoclonal antibody induced internalization of CD3 and CD4 antigens.
TL;DR: The results indicate that the mAb‐induced modulation of CD3 is essentially dependent on the PTK pathway, whereas PTK appear to negatively regulate the m Ab‐induced moduiation of CD4.
11
The use of monoclonal antibodies in allogeneic bone marrow transplantation
TL;DR: Allogeneic bone marrow transplantation (BMT) is one of the clinical fields where therapeutic use of monoclonal antibodies (MAb) has been frequently attempted during the last 10 years, based on a need for immunosuppressive reagents that are low in toxicity.
11
Two novel mutations responsible for hereditary type I protein C deficiency: characterization by denaturing gradient gel electrophoresis.
Sophie Gandrille,Michel Vidaud,Martine Aiach,Martine Alhenc-Gelas,Alain Fischer,M. Gouault-Heilman,Pierre Toulon,Jean-Noël Fiessinger,Michel Goossens +8 more
TL;DR: A strategy combining polymerase chain reaction amplification of selected gene fragments, denaturing gradient gel electrophoresis of the amplification products, and direct sequencing of fragments with altered melting behavior is studied, identifying two previously undescribed mutations located in exon VII.
11