Alain Enjalbert
Aix-Marseille University
156 Papers
2.1K Citations
Alain Enjalbert is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Somatostatin & Prolactin. The author has an hindex of 42, co-authored 156 publications. Previous affiliations of Alain Enjalbert include French Institute of Health and Medical Research & Collège de France.
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Papers
Imprinting of the Gsα gene GNAS1 in the pathogenesis of acromegaly
Bruce E. Hayward,Anne Barlier,Márta Korbonits,Ashley B. Grossman,Philippe Jacquet,Alain Enjalbert,David T. Bonthron +6 more
TL;DR: It is suggested that G(s)alpha imprinting is regulated separately from that of the other GNAS1 products, NESP55 and XLalphas, imprinting of which is retained in these tumors.
Angiotensin II and dopamine modulate both cAMP and inositol phosphate productions in anterior pituitary cells. Involvement in prolactin secretion.
Alain Enjalbert,F Sladeczek,Gilles Guillon,P. Bertrand,C. Shu,Jacques Epelbaum,A Garcia-Sainz,Serge Jard,C Lombard,Claude Kordon +9 more
TL;DR: It is concluded that angiotensin II and dopamine receptors of lactotroph cells are able to modulate both cAMP and inositol phosphate production.
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Macroprolactinemia revisited: a study on 106 patients.
Sophie Vallette-Kasic,I. Morange-Ramos,Adel Selim,G. Gunz,Sophie Morange,Alain Enjalbert,Pierre-Marie Martin,Philippe Jaquet,Thierry Brue +8 more
TL;DR: The incidence of macroprolactinemia in the hyperProlactinemic population was at least 10%, and despite preserved fertility with uneventful pregnancies, some of the usual symptoms of hyperprolactedine were present.
Genetic analysis in young patients with sporadic pituitary macroadenomas: besides AIP don't forget MEN1 genetic analysis
Thomas Cuny,Morgane Pertuit,M Sahnoun-Fathallah,Adrian Daly,Gianluca Occhi,Marie Françoise Odou,Antoine Tabarin,Marie Laure Nunes,Brigitte Delemer,Vincent Rohmer,Rachel Desailloud,Véronique Kerlan,Olivier Chabre,Jean-Louis Sadoul,M. Cogne,Philippe Caron,Christine Cortet-Rudelli,Anne Lienhardt,Isabelle Raingeard,Anne-Marie Guedj,Thierry Brue,Albert Beckers,Georges Weryha,Alain Enjalbert,Anne Barlier +24 more
TL;DR: Mutations in MEN1 can be of significance in young patients with sporadic isolated pituitary macroadenomas, particularly PRL, and together with AIP, are suggested to suggest genetic analysis of MEN1 in such a population.
Efficacy of chimeric molecules directed towards multiple somatostatin and dopamine receptors on inhibition of GH and prolactin secretion from GH-secreting pituitary adenomas classified as partially responsive to somatostatin analog therapy.
P. Jaquet,Ginette Gunz,Alexandru Saveanu,H. Dufour,John E. Taylor,J Z Dong,Sun H. Kim,J. P. Moreau,Alain Enjalbert,Michael D. Culler +9 more
TL;DR: Novel dopamine-somatostatin chimeric molecules with differing, enhanced activity at sstr2, sstr5 and DAD2, consistently produced significatly greater suppression of GH and PRL than either octreotide or single-receptor-interacting ligands in tumors from patients classified as only partially responsive toOctreotide therapy.