Hematologic manifestations associated with deletions of the long arm of chromosome 20

Chromosome studies in polycythemia vera patients

Chromosomal Changes in Human Tumors and Leukemias

Cytogenetic studies on acute nonlymphocytic leukemias following polycythemia vera

A family is described in which four out of five siblings have chromosomal aberrations both in the myeloid and lymphoid cells. One of these died in the blastic phase of chronic myelogenous leukemia, another had myelofibrosis and carcinoma of the breast, a third had squamous cell carcinoma of the lip, and the other two siblings are normal. The mother had carcinoma or the breast. Two of the siblings have had occupational exposure to organic solvents. The relationship of genetic pre-disposition to malignancy, chromosomal instability, and environmental stresses is discussed.

https://acsjournals.onlinelibrary.wiley.com/doi/epdf/10.1002/1097-0142%28197401%2933%3A1%3C72%3A%3AAID-CNCR2820330114%3E3.0.CO%3B2-8

Chromosomal aberrations and neoplasm--a family study.

Chromosomal Aberrations in Polycythemia Vera

Chromosomal aberrations reported in the disease course of patients with polycythemia vera are reviewed. Methodological pitfalls related to data collection, presentation and interpretation are pointed out. On the basis of the available information, it seems reasonable to conclude that chromosomal derangements are not specific to polycythemia vera and that clone formation is infrequent. The effect of therapy is manifested by an increase in the quantity of aberrations rather than in any specific type of aberration.

Cytogenetic findings in polycythemia vera: a review and reevaluation.

[The effects of chemical protection against radiation as reflected by aberrations of the chromosomes in the bone-marrow of mice after exposure to x-rays].

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Chromosomal Aberrations in Polycythemia Vera

Cytogenetic findings in polycythemia vera: a review and reevaluation.

[The effects of chemical protection against radiation as reflected by aberrations of the chromosomes in the bone-marrow of mice after exposure to x-rays].