Akshar Lohith
University of California, Santa Cruz
6 Papers
6 Citations
Akshar Lohith is an academic researcher from University of California, Santa Cruz. The author has contributed to research in topics: Neurite & Growth cone. The author has an hindex of 4, co-authored 6 publications.
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Papers
Determining the cause of recurrent Clostridium difficile infection using whole genome sequencing
James Heng Chiak Sim,Cynthia Truong,Samuel S. Minot,Nick Greenfield,Indre Budvytiene,Akshar Lohith,Victoria Anikst,Nader Pourmand,Niaz Banaei +8 more
TL;DR: The majority of CDI recurrences at this institution were due to infection with the same strain rather than infection with a new strain, indicating relapse with prior strain of C. difficile was the cause.
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High-Throughput Functional Annotation of Natural Products by Integrated Activity Profiling
Suzie K. Hight,Kenji L. Kurita,Elizabeth A. McMillan,Walter M. Bray,Trevor N. Clark,Anam F. Shaikh,F. P. Jake Haeckl,Fausto Carnevale-Neto,Scott La,Akshar Lohith,Rachel M. Vaden,Jeon Lee,Shuguang Wei,R. Scott Lokey,Michael A. White,Roger G. Linington,John B. MacMillan,John B. MacMillan +17 more
TL;DR: A comprehensive platform that uses Similarity Network Fusion (SNF) to improve MOA predictions by integrating data from the cytological profiling high-content imaging platform and the gene expression platform FUSION is reported.
Smartphone Operated Signal Transduction by Ion Nanogating (STING) Amplifier for Nanopore Sensors: Design and Analytical Application
Rıfat Emrah Özel,Sina Kahnemouyi,Hsinwen Fan,Wai H. Mak,Akshar Lohith,Adam R. Seger,Mircea Teodorescu,Nader Pourmand +7 more
TL;DR: To the best knowledge, STING amplifier is the first miniaturized wireless voltage-clamp platform operated with a customized smart-phone application (app) and it is proposed that this amplifier interfaces a sensing probe and connects wirelessly with a computer or smartphone for the required stimulus input, data processing and storage.
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Compartmental genomics in living cells revealed by single-cell nanobiopsy.
Paolo Actis,Michelle M. Maalouf,Hyunsung John Kim,Akshar Lohith,Boaz Vilozny,R. Adam Seger,Nader Pourmand +6 more
TL;DR: A single-cell nanobiopsy platform based on scanning ion conductance microscopy (SICM) for continuous sampling of intracellular content from individual cells is developed and may provide the foundation for dynamic subcellular genomic analysis.
Optimized Protocol for Simple Extraction of High-Quality Genomic DNA from Clostridium difficile for Whole-Genome Sequencing
TL;DR: An optimized method is described for the simple extraction of C. difficile gDNA using the QIAamp DNA minikit, which yielded high-quality sequence reads on the Illumina MiSeq platform.