Akinobu Hamada
National Cancer Research Institute
14 Papers
41 Citations
Akinobu Hamada is an academic researcher from National Cancer Research Institute. The author has contributed to research in topics: Erlotinib & Amrubicin. The author has an hindex of 4, co-authored 14 publications.
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Papers
Associations Between Elastography Findings and Clinicopathological Factors in Breast Cancer.
Mitsuhiro Hayashi,Yutaka Yamamoto,Aiko Sueta,Mai Tomiguchi,Mutsuko Yamamoto-Ibusuki,Teru Kawasoe,Akinobu Hamada,Hirotaka Iwase +7 more
TL;DR: It is identified that clinical tumor stiffness significantly correlated with lymph node involvement and invasive tumor size but not with hormonal receptor expressions, human epidermal growth factor receptor type 2 status, and ki67 labeling index by analyses of both categorical and continuous variables of stiffness.
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Comparison of the pharmacokinetics of erlotinib administered in complete fasting and 2 h after a meal in patients with lung cancer
Yuki Katsuya,Yutaka Fujiwara,Kuniko Sunami,Hirofumi Utsumi,Yasushi Goto,Shintaro Kanda,Hidehito Horinouchi,Hiroshi Nokihara,Noboru Yamamoto,Yuki Takashima,Satoko Osawa,Yuichiro Ohe,Tomohide Tamura,Akinobu Hamada +13 more
TL;DR: The AUC0–24 increased significantly faster in the 2-h post-meal status than in complete fasting status, which suggested that the two gastric emptying states might differ in their absorption, but there was no clinically significant difference in bioavailability or toxicity between the two clinically used fed conditions.
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The Long Half-Life of Programmed Cell Death Protein 1 Inhibitors May Increase the Frequency of Immune-Related Adverse Events After Subsequent EGFR Tyrosine Kinase Inhibitor Therapy.
Yuki Shinno,Yasushi Goto,Mayu Ohuchi,Akinobu Hamada,Hiroshi Nokihara,Yasuhiro Fujiwara,Yuichiro Ohe +6 more
- 01 Mar 2020
TL;DR: The presence of the ICI antibody that persists even after drug discontinuation may account not only for the prolonged efficacy of these agents but also for the late onset of AEs, especially when the antibodies may have interacted during subsequent treatments.
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Patent
Sample adjustment method for mass spectrometric analysis, and mass spectrometry
秀一 新間,Shuichi Niima,哲暢 濱田,Akinobu Hamada +3 more
- 10 Apr 2013
TL;DR: In this article, a matrix support laser desorption ionization method (MALDI) is used for sample adjustment for mass spectrometric analysis of a biological sample for medical applications.
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Extension of the Calvert formula to patients with severe renal insufficiency
Tomoyo Oguri,Tomoya Shimokata,Isao Ito,Yoshinari Yasuda,Naoto Sassa,Masami Nishiyama,Akinobu Hamada,Yoshinori Hasegawa,Yuichi Ando +8 more
TL;DR: For adult patients with severe renal insufficiency, the Calvert formula causes carboplatin overdosing by overestimating thecarboplatin clearance.
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