Ajay Bommareddy
Wilkes University
40 Papers
415 Citations
Ajay Bommareddy is an academic researcher from Wilkes University. The author has contributed to research in topics: Apoptosis & Cancer. The author has an hindex of 19, co-authored 36 publications. Previous affiliations of Ajay Bommareddy include University of Pittsburgh & South Dakota State University.
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Papers
Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells.
Shivendra V. Singh,Renaud Warin,Dong Xiao,Anna A. Powolny,Silvia D. Stan,Julie A. Arlotti,Yan Zeng,Eun-Ryeong Hahm,Stanley W. Marynowski,Ajay Bommareddy,Dhimant Desai,Shantu Amin,Robert A. Parise,Jan H. Beumer,William H. Chambers +14 more
TL;DR: The results of the present study indicate that SFN administration inhibits prostate cancer progression and pulmonary metastasis in TRAMP mice by reducing cell proliferation and augmenting NK cell lytic activity.
202
Chemopreventive effects of dietary flaxseed on colon tumor development.
TL;DR: Dietary flaxseed meal containing high levels of ω-3 fatty acids and lignans is effective in preventing colon tumor development when compared with dietary corn meal possibly by increasing ω -3 fatty acid levels and decreasing COX-1 andCOX-2 levels.
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Cellular Responses to Cancer Chemopreventive Agent D, L-Sulforaphane in Human Prostate Cancer Cells Are Initiated by Mitochondrial Reactive Oxygen Species
Dong Xiao,Anna A. Powolny,Jedrzej Antosiewicz,Eun-Ryeong Hahm,Ajay Bommareddy,Yan Zeng,Dhimant Desai,Shantu Amin,Anna Herman-Antosiewicz,Shivendra V. Singh +9 more
TL;DR: It is indicated, for the first time, that mitochondria-derived ROS serve to initiate diverse cellular responses to SFN exposure in human prostate cancer cells.
Garlic Constituent Diallyl Trisulfide Prevents Development of Poorly Differentiated Prostate Cancer and Pulmonary Metastasis Multiplicity in TRAMP Mice
Shivendra V. Singh,Anna A. Powolny,Silvia D. Stan,Dong Xiao,Julie A. Arlotti,Renaud Warin,Eun-Ryeong Hahm,Stanley W. Marynowski,Ajay Bommareddy,Douglas M. Potter,Rajiv Dhir +10 more
TL;DR: DATS administration prevents progression to invasive carcinoma and lung metastasis in TRAMP mice for the first time, and does not have any appreciable effect on apoptosis induction, angiogenesis, or natural killer and dendritic cell function.
Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanate
TL;DR: In vivo anti‐cancer efficacy of BITC is demonstrated against MDA‐MB‐231 xenografts in association with reduced cell proliferation and suppression of neovascularization.