Aileen E. Olsen
University of Utah
8 Papers
26 Citations
Aileen E. Olsen is an academic researcher from University of Utah. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 8, co-authored 8 publications. Previous affiliations of Aileen E. Olsen include Huntsman Cancer Institute.
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Papers
Defects in SPT16 or POB3 (yFACT) in Saccharomyces cerevisiae cause dependence on the Hir/Hpc pathway: polymerase passage may degrade chromatin structure.
Tim Formosa,Susan Ruone,Melissa D. Adams,Aileen E. Olsen,Peter Eriksson,Yaxin Yu,Alison R. Rhoades,Paul D. Kaufman,David J. Stillman +8 more
TL;DR: In this article, Spt16/Cdc68, Pob3, and Nhp6 collaborate in vitro and in vivo as the yeast factor SPN, which is homologous to human FACT.
Chromosome-scale genetic mapping using a set of 16 conditionally stable Saccharomyces cerevisiae chromosomes.
Robert J.D. Reid,Ivana Sunjevaric,Warren P. Voth,Samantha Ciccone,Wendy Du,Aileen E. Olsen,David J. Stillman,Rodney Rothstein +7 more
TL;DR: It is shown that the 16 yeast chromosomes can be individually lost in diploid strains, which become hemizygous for the destabilized chromosome, and most 2n − 1 strains endoduplicate and become 2n.
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Molecular cloning and subcellular distribution of the novel PDE4B4 cAMP-specific phosphodiesterase isoform.
Malcolm Shepherd,Theresa McSorley,Aileen E. Olsen,Lee Ann Johnston,Neil C. Thomson,George S. Baillie,Miles D. Houslay,Graeme B. Bolger +7 more
TL;DR: RNase protection demonstrated that PDE4B4 mRNA is expressed preferentially in liver, skeletal muscle and various regions of the brain, which differs from the pattern of tissue distribution of the other known PDE 4B long forms.
Human PDE4A8, a novel brain-expressed PDE4 cAMP-specific phosphodiesterase that has undergone rapid evolutionary change
Kirsty F. MacKenzie,Emma C. Topping,Bozena Bugaj-Gaweda,Chengjun Deng,York-Fong Cheung,Aileen E. Olsen,Cecil R. Stockard,Lisa High Mitchell,George S. Baillie,William E. Grizzle,Michael De Vivo,Miles D. Houslay,Daguang Wang,Graeme B. Bolger,Graeme B. Bolger +14 more
TL;DR: Immunohistochemical analysis showed that PDE4A8 could be detected in discrete regions of human brain, including the cerebellum, spinal cord and cerebral cortex, suggesting that this isoform may have a specific function in regulating cAMP levels in human skeletal muscle and brain.
ACE2, CBK1, and BUD4 in budding and cell separation.
TL;DR: It is shown that an ACE2 multicopy plasmid suppresses the latter three defects of RAM network mutations, demonstrating that Ace2 is downstream of the RAM network and suggesting that these phenotypes are caused by reduced expression of Ace2 target genes.