Ahmad Othman
Rush University Medical Center
11 Papers
74 Citations
Ahmad Othman is an academic researcher from Rush University Medical Center. The author has contributed to research in topics: Cancer research & Breast cancer. The author has an hindex of 4, co-authored 7 publications. Previous affiliations of Ahmad Othman include University of Illinois at Chicago.
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Papers
Olig1 is expressed in human oligodendrocytes during maturation and regeneration.
Ahmad Othman,David M. Frim,Paul E. Polak,Snezana Vujicic,Barry G. W. Arnason,Anne I. Boullerne +5 more
TL;DR: The findings point to different roles of Olig1 and Olig2 in regeneration of cultured adult human oligodendrocytes, Noticeably, the transcriptional profiles found in cultured neonatal rodent OPC are different.
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Bone Metastatic Breast Cancer: Advances in Cell Signaling and Autophagy Related Mechanisms.
TL;DR: The role of the autophagy and secretory pathways in interactions between resident and tumor cells during bone metastatic tumor growth was highlighted in this article. But, the role of these pathways in the development of bone metastasis remains poorly understood.
17
Transcriptional regulation of the human Na+/H+ exchanger NHE3 by serotonin in intestinal epithelial cells.
Ruhul Amin,Leda Ghannad,Ahmad Othman,Ravinder K. Gill,Pradeep K. Dudeja,Krishnamurthy Ramaswamy,Jaleh Malakooti +6 more
TL;DR: The data indicate that 5-HT suppresses the transcriptional activity of the NHE3 promoter and this effect may be mediated by PKCalpha and modulation of DNA-binding affinities of Sp1 and Sp3.
16
Bone metastatic breast cancer cells display downregulation of PKC-ζ with enhanced glutamine metabolism
TL;DR: In this paper, the expression levels of genes related to metabolism were examined by PCR arrays and the genes involved in serine biosynthesis pathway genes and protein kinase C zeta (PKC-ζ) expression levels in bone-derived MDA-MB-231 cells compared to the parental population.
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The Role of Runx2 in Microtubule Acetylation in Bone Metastatic Breast Cancer Cells
TL;DR: The results indicate a novel regulatory mechanism of microtubule acetylation and suggest that Runx2 and acetylated microtubules may serve as therapeutic targets for bone metastatic tumors.