Adnan Ali
German Cancer Research Center
3 Papers
Adnan Ali is an academic researcher from German Cancer Research Center. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 3, co-authored 3 publications.
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Papers
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer
Mohsen Malehmir,Dominik Pfister,Suchira Gallage,Marta Szydlowska,Donato Inverso,Donato Inverso,Elena Kotsiliti,Elena Kotsiliti,Valentina Leone,Moritz Peiseler,Bas G.J. Surewaard,Dominik Rath,Adnan Ali,Monika Julia Wolf,Hannah K. Drescher,Marc E. Healy,Daniel Dauch,Daniela C. Kroy,Oliver Krenkel,Marlene Kohlhepp,Thomas Engleitner,Thomas Engleitner,Alexander Olkus,Alexander Olkus,Tjeerd P. Sijmonsma,Julia Volz,Carsten Deppermann,David Stegner,Patrick M. Helbling,César Nombela-Arrieta,Anahita Rafiei,Martina Hinterleitner,Marcel Rall,Florian Baku,Oliver Borst,Caroline L. Wilson,Jack Leslie,Tracy O'Connor,Christopher J. Weston,David H. Adams,Lozan Sheriff,Ana Teijeiro,Marco Prinz,Ruzhica Bogeska,Natasha S Anstee,Malte N. Bongers,Mike Notohamiprodjo,Tobias Geisler,Dominic J. Withers,Jerry Ware,Derek A. Mann,Hellmut G. Augustin,Hellmut G. Augustin,Alexandros Vegiopoulos,Michael D. Milsom,Adam J. Rose,Patricia F. Lalor,Josep M. Llovet,Josep M. Llovet,Josep M. Llovet,Roser Pinyol,Frank Tacke,Roland Rad,Roland Rad,Matthias S. Matter,Nabil Djouder,Paul Kubes,Percy A. Knolle,Kristian Unger,Lars Zender,Lars Zender,Bernhard Nieswandt,Meinrad Gawaz,Achim Weber,Mathias Heikenwalder,Mathias Heikenwalder +75 more
TL;DR: It is shown that platelet number, platelet activation and platelet aggregation are increased in NASH but not in steatosis or insulin resistance, offering a potential approach to treat non-alcoholic steatohepatitis and prevent subsequent progression to hepatocellular carcinoma.
CD8+ T cells induce cachexia during chronic viral infection.
Hatoon Baazim,Martina Schweiger,Michael Moschinger,Haifeng Xu,Thomas Scherer,Alexandra Popa,Suchira Gallage,Adnan Ali,Kseniya Khamina,Lindsay Kosack,Bojan Vilagos,Mark J. Smyth,Alexander Lercher,Joachim Friske,Doron Merkler,Alan Aderem,Thomas H. Helbich,Mathias Heikenwalder,Philipp A. Lang,Rudolf Zechner,Andreas Bergthaler +20 more
TL;DR: A model of reversible cachexia in mice with chronic viral infection is described and an essential role for CD8+ T cells is identified in infection-associated cachexia, which is dependent on T cell–intrinsic type I IFN signaling and antigen recognition.
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Liver Inflammation and Hepatobiliary Cancers.
TL;DR: This review discusses the link between oxidative stress and the hepatic immune compartments, as well as how these factors trigger hepatocyte damage, proliferation, and eventually cancer initiation and its sustainment and an overview of new anticancer therapies based on immunomodulation.
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