Adiv A. Johnson
Mayo Clinic
37 Papers
129 Citations
Adiv A. Johnson is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Biology & Bestrophin 1. The author has an hindex of 17, co-authored 33 publications. Previous affiliations of Adiv A. Johnson include University of Arizona & Vision-Sciences, Inc..
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Papers
The role of DNA methylation in aging, rejuvenation, and age-related disease
Adiv A. Johnson,Kemal Akman,Stuart R. G. Calimport,Daniel Wuttke,Alexandra Stolzing,João Pedro de Magalhães +5 more
TL;DR: DNMTs, demethylases, and associated partners are dynamically shaping the methylome and demonstrate great promise with regard to rejuvenation.
The role of lipid metabolism in aging, lifespan regulation, and age‐related disease
TL;DR: The data suggest that lipid‐related interventions may improve human healthspan and that blood lipids likely represent a rich source of human aging biomarkers.
334
Bestrophin 1 and retinal disease.
Adiv A. Johnson,Adiv A. Johnson,Karina E Guziewicz,C. Justin Lee,Ravi C. Kalathur,Jose S. Pulido,Lihua Y. Marmorstein,Alan D. Marmorstein +7 more
TL;DR: Prospects for near-term clinical trials to test therapies for the bestrophinopathies, a currently incurable and untreatable set of diseases, are discussed.
213
The impact of larval and adult dietary restriction on lifespan, reproduction and growth in the mosquito Aedes aegypti
TL;DR: It is demonstrated that diet restriction during either larval or adult stages extends Aedes aegypti lifespan, and this diet-mediated lifespan extension has important consequences for understanding how dietary restriction regulates lifespan and disease transmission.
124
Systematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age.
TL;DR: A novel proteomic aging clock comprised of proteins that were reported to change with age in plasma in three or more different studies is proposed and it is demonstrated that this clock is able to accurately predict human age.
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