Adem Guven

TL;DR: Sub-micrometer discoidal magnetic nanoconstructs are realized by confining 5 nm ultra-small super-paramagnetic iron oxide nanoparticles within two different mesoporous structures, made out of silicon and polymers, which collectively cooperate to amplify tumor accumulation in tumor bearing mice.

TL;DR: The ability of the US-tube platform to promote the delivery of encapsulated CDDP by increasing the accumulation of drug in breast cancer resistance cells is demonstrated, which reveals how CDDP@US-tubes help overcome CDDP resistance.

TL;DR: It is demonstrated that highly water-dispersed graphene nanoribbons dispersed by carboxyphenylated substituents and conjugated to aquated Gd(3+) ions can serve as a high-performance contrast agent for applications in T1- and T2-weighted magnetic resonance imaging (MRI) with relaxivity values outperforming currently-available clinical CAs.

TL;DR: It is demonstrated here that non-invasive radiofrequency field activation of the CDDP@US-tubes produces heat that causes Pluronic disruption which triggers cisplatin release in an RF-dependent manner, and release-dependent cytotoxicity is demonstrated in human hepatocellular carcinoma cell lines.