Adam Warner
University of British Columbia
10 Papers
36 Citations
Adam Warner is an academic researcher from University of British Columbia. The author has contributed to research in topics: Caenorhabditis elegans & Myofilament. The author has an hindex of 8, co-authored 10 publications. Previous affiliations of Adam Warner include University of Washington.
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Papers
An integrated strategy to study muscle development and myofilament structure in Caenorhabditis elegans.
Barbara Meissner,Adam Warner,Kim Wong,Nicholas Dube,Adam Lorch,Sheldon J. McKay,Jaswinder Khattra,Teresa M. Rogalski,Aruna Somasiri,Iasha Chaudhry,Rebecca M. Fox,David M. Miller,David L. Baillie,Robert A. Holt,Steven J.M. Jones,Marco A. Marra,Donald G. Moerman +16 more
TL;DR: It is proposed that additional sarcomeric proteins exist for which there is a less severe, or entirely different, mutant phenotype produced in their absence from late embryonic muscle gene expression.
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CPNA-1, a copine domain protein, is located at integrin adhesion sites and is required for myofilament stability in Caenorhabditis elegans
Adam Warner,Ge Xiong,Hiroshi Qadota,Teresa M. Rogalski,A. Wayne Vogl,Donald G. Moerman,Guy M. Benian +6 more
TL;DR: A new integrin-associated protein, CPNA-1, which is essential for embryonic muscle development, is characterized and contains a C-terminal copine domain.
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The Caenorhabditis elegans paxillin orthologue, PXL-1, is required for pharyngeal muscle contraction and for viability.
TL;DR: Caenorhabditis elegans pxl-1 is the orthologue of vertebrate paxillin and is expressed in body wall and pharyngeal muscle and PXL- 1 is required in the pharynx for muscle contraction and viability.
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•Journal Article
CPNA-1, a Copine Domain Protein, Is Located at Integrin Adhesion Sites, and Is Required for Myofilament Stability in C. elegans (P07.037)
TL;DR: A novel essential muscle gene cpna-1 has been identified and it is proposed that CPNA-1 acts as a linker between integrin associated protein PAT-6 and downstream components to play a role in myofilament stability.
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The role of PXL-1 and CPNA-1 in the organization of muscle adhesion complexes in Caenorhabditis elegans muscle
Adam Warner
- 01 Jan 2012
TL;DR: A comparison of C. elegans body wall muscle and vertebrate muscle and the PXL-1 pathway shows that the former is a better model organism for muscle attachment complexes while the latter is a poor candidate for attachment complexes.
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