The present invention provides systems, devices, signaling polynucleotides (SPNs), detection agents and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sampler, at least one disposable detection vessel for receiving and processing a test sample and a detection device for measuring a fluorescent signal. SPNs derived from aptamer that bind allergens are also provided as allergen detection agents. SPNs have a single open structure, and are probed with a fluorophore. Changes in fluorescence polarization of detection agents upon the binding of allergens are measured to calculate the allergen content in a sample.

Systems and methods for allergen detection

The present invention relates to a disaggregation and homogenization device also capable of photoactivation to improve heat resilience, photoactivation efficiency and simultaneous processing. In the disclosed invention processes of disaggregation and homogenization may be handled in a simultaneous manner at will. Moreover, in various embodiments of the disclosed invention, a photoactivation means is present, rendering simultaneous utility of photoactivation and homogenization possible, eliminating extra steps for preparation. Protocols of both processes are registerable and adjustable in parameters i.e. rate of revolution and duration of process overall; executed through an electronic control unit capable of storing and executing said protocols.

A tissue disaggregation, homogenization, photoactivation device

This disclosure pertains to a testing method for a target pathogen. The method uses biosensors with particular fluorescence characteristics, such that when the biosensor binds to a target pathogen, a fluorophore may emit light if excited. The biosensor may be an aptamer-based biosensor with a fluorophore reporter and a quencher. The excitation of the fluorophore and the detection of fluorescence may be made through the use of a flashlight source and a camera from a mobile device, such as a smartphone.

Pathogen detection using aptamer molecular beacons using a mobile device

The present disclosure relates to a novel analyte detection device and methods for detecting analytes of interest, such as allergens. In particular, the present disclosure provides a portable analyte detection device that is intended for on-site use by consumers. A fused split peroxidase-analyte binder complex is disclosed having a split peroxidase in at least two fragments, each fused to an analyte binder fragment capable of binding an analyte of interest.

Analyte detection method and device

This invention relates to methods and materials for functional ligands, particularly to methods and materials for utilizing structure-switching functional ligands which bind to a target, more particularly to methods and materials for utilizing structure-switching functional ligands which modulate the activity of a signal-interacting pair by binding to a target and further particularly to methods and materials for utilizing structure-switching functional ligands to release signal-interacting molecules to produce a detectable signal indicative of the presence and/or amount of a target in a sample.

Detection of tenofovir

The present invention is drawn to devices and systems for allergen detection in a sample. The allergen detection system includes a sampler, a disposable analysis cartridge and a detection device with an optimized optical system. In some embodiments, the allergen detection utilizes aptamer nucleic acid molecules as detection agents. In some embodiments, the nucleic acids are conjugated to magnetic beads or solid surfaces such as glasses, microwells and microchips.

Systems for allergen detection

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Systems and methods for allergen detection

Systems for allergen detection