Adam J. Ratner
New York University
146 Papers
811 Citations
Adam J. Ratner is an academic researcher from New York University. The author has contributed to research in topics: Streptococcus agalactiae & Biology. The author has an hindex of 39, co-authored 130 publications. Previous affiliations of Adam J. Ratner include Columbia University Medical Center & Columbia University.
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Papers
Multisystem Inflammatory Syndrome in U.S. Children and Adolescents.
Leora R. Feldstein,Leora R. Feldstein,Erica B. Rose,Erica B. Rose,Steven M. Horwitz,Jennifer P. Collins,Margaret M Newhams,Mary Beth F. Son,Jane W. Newburger,Lawrence C. Kleinman,Sabrina M. Heidemann,Amarilis A. Martin,Aalok R. Singh,Simon Li,Keiko M. Tarquinio,Preeti Jaggi,Matthew E. Oster,Sheemon P. Zackai,Jennifer K. Gillen,Adam J. Ratner,Rowan Walsh,Julie C. Fitzgerald,Michael A. Keenaghan,Hussam Alharash,Sule Doymaz,Katharine N. Clouser,John S. Giuliano,Anjali Gupta,Robert M. Parker,Aline B Maddux,Vinod Havalad,Stacy Ramsingh,Hulya Bukulmez,Tamara T. Bradford,Lincoln S. Smith,Mark W Tenforde,Christopher L. Carroll,Becky J. Riggs,Shira J. Gertz,Ariel Daube,Amanda N Lansell,Alvaro Coronado Munoz,Charlotte V. Hobbs,Kimberly Marohn,Natasha B. Halasa,Manish M. Patel,Manish M. Patel,Adrienne G. Randolph +47 more
TL;DR: Multisystem inflammatory syndrome in children associated with SARS-CoV-2 led to serious and life-threatening illness in previously healthy children and adolescents.
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The Ngal Reporter Mouse Detects the Response of the Kidney to Injury in Real Time
Neal Paragas,Andong Qiu,Qing-Yin Zhang,Benjamin Samstein,Shi-Xian Deng,Kai M. Schmidt-Ott,Mélanie Viltard,Wenqiang Yu,Catherine S. Forster,Gangli Gong,Yidong Liu,Ritwij Kulkarni,Kiyoshi Mori,Avtandil Kalandadze,Adam J. Ratner,Prasad Devarajan,Donald W. Landry,Vivette D. D'Agati,Chyuan-Sheng Lin,Jonathan Barasch +19 more
TL;DR: In the kidney, Ngal-Luc2-mC imaging showed a sensitive, rapid, dose-dependent, reversible, and organ- and cell-specific relationship with tubular stress, which correlated with the level of urinary Ngal (uNgal), and specific cells of the distal nephron were the source of uNgal.
Role of Pore-Forming Toxins in Bacterial Infectious Diseases
TL;DR: Common functions of PFTs include disruption of epithelial barrier function and evasion of host immune responses, which contribute to bacterial growth and spreading, make this group of toxins an attractive target for the development of new virulence-targeted therapies that may have broad activity against human pathogens.
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Detection of severe acute respiratory syndrome coronavirus 2 in placental and fetal membrane samples.
Christina A. Penfield,Sara G. Brubaker,Meghana Limaye,Jennifer Lighter,Adam J. Ratner,Kristen Thomas,Jessica A. Meyer,Ashley S. Roman +7 more
- 08 May 2020
TL;DR: This is the first study to demonstrate the presence of SARS-CoV-2 RNA in placental or membrane samples and raise the possibility of intrapartum viral exposure.
Iron traffics in circulation bound to a siderocalin (Ngal)–catechol complex
Guan-Hu Bao,Matthew S Clifton,Trisha M. Hoette,Trisha M. Hoette,Kiyoshi Mori,Shi-Xian Deng,Andong Qiu,Mélanie Viltard,David S. Williams,Neal Paragas,Thomas Leete,Ritwij Kulkarni,Xiangpo Li,Belinda T. Lee,Avtandil Kalandadze,Adam J. Ratner,Juan C. Pizarro,Kai M. Schmidt-Ott,Donald W. Landry,Kenneth N. Raymond,Kenneth N. Raymond,Roland K. Strong,Jonathan Barasch +22 more
TL;DR: Using chemical screens, crystallography, and fluorescence methods, it is reported that Scn-Ngal binds iron together with a small metabolic product called catechol, which represents an unforeseen microbial-host interaction, which mimics Scsiderophore interactions, but instead traffics iron in aseptic tissues.
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