Abhalaxmi Singh
Nalco Holding Company
23 Papers
68 Citations
Abhalaxmi Singh is an academic researcher from Nalco Holding Company. The author has contributed to research in topics: Drug delivery & Medicine. The author has an hindex of 10, co-authored 19 publications. Previous affiliations of Abhalaxmi Singh include Northwestern University & University of Illinois at Chicago.
Chat about Author
Papers
Magnetic nanoparticles: a novel platform for cancer theranostics.
Abhalaxmi Singh,Sanjeeb K. Sahoo +1 more
TL;DR: In this review, the different theranostic applications of MNPs are discussed and the current challenges associated with the clinical translation ofMNPs are raised along with future opportunities in this field.
299
Composite polymeric magnetic nanoparticles for co-delivery of hydrophobic and hydrophilic anticancer drugs and MRI imaging for cancer therapy.
Abhalaxmi Singh,Fahima Dilnawaz,Sujeet Mewar,Uma Sharma,Naranamangalam R. Jagannathan,Sanjeeb K. Sahoo +5 more
TL;DR: The results demonstrated the dual usable purpose of formulated PLGA-MNPs toward either, in therapeutics by delivering different hydrophobic or hydrophilic drugs individually or in combination and imaging for cancer therapeutics in the near future.
165
The transport of non-surfactant based paclitaxel loaded magnetic nanoparticles across the blood brain barrier in a rat model
Fahima Dilnawaz,Abhalaxmi Singh,Sujeet Mewar,Uma Sharma,Naranamangalam R. Jagannathan,Sanjeeb K. Sahoo +5 more
TL;DR: The significant prevalence of drugs in the rat brain tissues, in vitro targeting potentiality as well as the augmented contrast effect elicit the non-invasive assessment and theranostic applications of MNPs for brain tumor therapy.
91
Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis
Abhalaxmi Singh,Sreeparna Chakraborty,Sing Wan Wong,Nicole A Hefner,A. Stuart,Abdul S Qadir,Amitabha Mukhopadhyay,Kurt Bachmaier,Jae-Won Shin,Jalees Rehman,Asrar B. Malik +10 more
TL;DR: The results show that engineered mannosylated albumin nanoparticles specifically targeted disease-inducing Mo-Macs, and further, that nanoparticles efficiently delivered small-interfering RNA against profibrotic cytokine tumor growth factor β1 to prevent bleomycin-induced lung fibrosis.
58
Long circulating lectin conjugated paclitaxel loaded magnetic nanoparticles: a new theranostic avenue for leukemia therapy.
TL;DR: In vitro and in vivo results strongly suggested the pac-MNPs as a future prospective theranostic tool for leukemia therapy and the potential application of MNPs as imaging agent.