Abdul Wakeel
University of Texas Medical Branch
13 Papers
24 Citations
Abdul Wakeel is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Ehrlichia chaffeensis & Tandem repeat. The author has an hindex of 10, co-authored 13 publications. Previous affiliations of Abdul Wakeel include Jawaharlal Nehru University.
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Papers
Nuclear translocated Ehrlichia chaffeensis ankyrin protein interacts with a specific adenine-rich motif of host promoter and intronic Alu elements
TL;DR: It is determined by confocal immunofluorescence microscopy and by immunodetection in purified nuclear extracts that the ankyrin repeat-containing protein p200 is translocated to the nuclei of Ehrlichia-infected monocytes, the first study to identify a nuclear translocation of bacterially encoded protein by E. chaffeensis.
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Novel MRI Contrast Agent from Magnetotactic Bacteria Enables In Vivo Tracking of iPSC-derived Cardiomyocytes.
Morteza Mahmoudi,Morteza Mahmoudi,Atsushi Tachibana,Andrew B. Goldstone,Y. Joseph Woo,Papia Chakraborty,Kayla R. Lee,Chandler S. Foote,Stephanie Piecewicz,Joyce C. Barrozo,Abdul Wakeel,Bradley W. Rice,Caleb B. Bell,Phillip C. Yang +13 more
TL;DR: The use of a living contrast agent, magneto-endosymbionts (MEs) derived from magnetotactic bacteria for the labeling of iCMs is demonstrated and will accelerate the clinical translation of in vivo MRI monitoring of transplanted stem cell at high spatial resolution and sensitivity.
Mass Spectrometric Analysis of Ehrlichia chaffeensis Tandem Repeat Proteins Reveals Evidence of Phosphorylation and Absence of Glycosylation
TL;DR: This study provides evidence that the N-terminal region of the TRP47 is tyrosine phosphorylated, which is responsible for larger-than-predicted masses in native and recombinant TRP32.
Characterization of Magneto-Endosymbionts as MRI Cell Labeling and Tracking Agents.
Kimberly D. Brewer,Kimberly D. Brewer,Ryan Spitler,Kayla R. Lee,Andrea C. Chan,Joyce C. Barrozo,Abdul Wakeel,Chandler S. Foote,Steven Machtaler,James A. Rioux,James A. Rioux,Juergen K. Willmann,Papia Chakraborty,Bradley W. Rice,Christopher H. Contag,Caleb B. Bell,Brian K. Rutt +16 more
TL;DR: The results demonstrate the potential of magneto-endosymbionts as living MR contrast agents, and provide strong MR contrast when loaded into cells and implanted in tissue, and have r2 relaxivity values comparable to traditional iron oxide nanoparticle contrast agents.
Cell Labeling with Magneto-Endosymbionts and the Dissection of the Subcellular Location, Fate, and Host Cell Interactions
Kayla R. Lee,Abdul Wakeel,Papia Chakraborty,Chandler S. Foote,Lauren Kajiura,Joyce C. Barrozo,Andrea C. Chan,Alexey V. Bazarov,Ryan Spitler,Peter M. Kutny,James M Denegre,Robert A. Taft,Joachim Seemann,Bradley W. Rice,Christopher H. Contag,Brian K. Rutt,Caleb B. Bell +16 more
TL;DR: MEs are used to label mammalian cells for the purpose of cell tracking in vivo, with MRI, and identification of the specific processes involved in ME clearance provides a framework to develop MEs with enhanced retention in mammalian cells.