Abdul Rahim
Indian Institute of Chemical Technology
8 Papers
26 Citations
Abdul Rahim is an academic researcher from Indian Institute of Chemical Technology. The author has contributed to research in topics: Indole test & Steglich esterification. The author has an hindex of 5, co-authored 6 publications. Previous affiliations of Abdul Rahim include Academy of Scientific and Innovative Research.
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Papers
Iodine mediated oxidative cross-coupling of unprotected anilines and heteroarylation of benzothiazoles with 2-methylquinoline
Abdul Rahim,Siddiq Pasha Shaik,Siddiq Pasha Shaik,Mirza Feroz Baig,Mirza Feroz Baig,Abdullah Alarifi,Ahmed Kamal +6 more
TL;DR: This work provides the first site-selective approach for the synthesis of free amino groups containing methanones including unprecedented C-H functionalization rather than the N-Hfunctionalization of unprotected anilines via the Kornblum oxidation of 2-methylquinoline.
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First total synthesis of the E- and Z-isomers of cytospolide-D
TL;DR: In this article, a simple convergent and efficient approach for the total synthesis of the bioactive E and Z-isomers of cytospolide-D is described, and the key features of the synthetic strategy include stereoselective methylation, regi-lective epoxide opening, olefin cross-metathesis, and a Yamaguchi protocol reaction for the formation of the E-olefinic geometry of the 10 membered ring.
15
Synthesis and biological evaluation of phenyl-amino-pyrimidine and indole/oxindole conjugates as potential BCR-ABL inhibitors
Abdul Rahim,Abdul Rahim,Riyaz Syed,Yedla Poornachandra,M. Shaheer Malik,Ch. Venkata Ramana Reddy,Mallika Alvala,Kiran Boppana,B. Sridhar,Ramars Amanchy,Ahmed Kamal,Ahmed Kamal +11 more
TL;DR: Indole/isatin conjugated phenyl-amino-pyrimidine derivatives have been synthesized, characterized and evaluated in vitro for their potential as BCR-ABL inhibitors and all derivatives were found to be more cytotoxic than standard Imatinib against K-562 cell line.
7
First Total Synthesis of the E‐ and Z‐Isomers of Cytospolide‐D.
TL;DR: In this paper, a simple convergent and efficient approach for the total synthesis of the bioactive E and Z-isomers of cytospolide-D is described, and the key features of the synthetic strategy include stereoselective methylation, regi-lective epoxide opening, olefin cross-metathesis, and a Yamaguchi protocol reaction for the formation of the E-olefinic geometry of the 10 membered ring.
Tankyrase inhibitors as therapeutic targets for cancer.
TL;DR: The current review covers the progress, mechanism and binding modes of recently known Tankyrase inhibitor and discusses the rational approaches that were used to identify the tankyrase inhibitors.