Aaron Wise
Carnegie Mellon University
14 Papers
30 Citations
Aaron Wise is an academic researcher from Carnegie Mellon University. The author has contributed to research in topics: Gene regulatory network & Biology. The author has an hindex of 6, co-authored 14 publications. Previous affiliations of Aaron Wise include Illumina.
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Papers
A transcription factor hierarchy defines an environmental stress response network
Liang Song,Shao-shan Carol Huang,Aaron Wise,Rosa Castanon,Joseph R. Nery,Huaming Chen,Marina Watanabe,Jerushah Thomas,Ziv Bar-Joseph,Joseph R. Ecker +9 more
TL;DR: It is proposed that dynamic, multi-TF binding could be a criterion for prioritizing the characterization of TF binding events, cis-regulatory elements, and functionally unknown genes in both plants and other species.
Integrated multi-omics framework of the plant response to jasmonic acid
Mark Zander,Mathew G. Lewsey,Mathew G. Lewsey,Natalie M. Clark,Lingling Yin,Lingling Yin,Anna Bartlett,J. Paola Saldierna Guzmán,J. Paola Saldierna Guzmán,Elizabeth Hann,Elizabeth Hann,Amber E. Langford,Bruce Jow,Aaron Wise,Joseph R. Nery,Huaming Chen,Ziv Bar-Joseph,Justin W. Walley,Roberto Solano,Joseph R. Ecker +19 more
TL;DR: This work investigated the signalling pathway of the hormone jasmonic acid (JA), which controls a plethora of critically important processes in plants and is orchestrated by the transcription factor MYC2 and its closest relatives in Arabidopsis thaliana, and generated an integrated framework of the response to JA.
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HERVs establish a distinct molecular subtype in stage II/III colorectal cancer with poor outcome.
Mahdi Golkaram,Michael L. Salmans,Shannon Kaplan,Raakhee Vijayaraghavan,Marta Martins,Nafeesa Khan,Cassandra Garbutt,Aaron Wise,Joyee Yao,Sandra Casimiro,Catarina Abreu,Daniela Macedo,Ana Lúcia Costa,C. Alvim,André Mansinho,Pedro Filipe,Pedro Marques da Costa,Afonso Fernandes,Paula Borralho,Cristina Ferreira,Fernando Aldeia,João Malaquias,Jim Godsey,Alex So,Traci Pawlowski,Luis Costa,Shile Zhang,Li Liu +27 more
TL;DR: In this article, the median expression of human endogenous retroviruses (hERVs) was used as a potential biomarker for prognosis, relapse, and resistance to chemotherapy in stage II and III colorectal cancer.
Carbon catabolite repression correlates with the maintenance of near invariant molecular crowding in proliferating E. coli cells
Yi Zhou,Alexei Vazquez,Aaron Wise,Tomoko Warita,Katsuhiko Warita,Ziv Bar-Joseph,Zoltán N. Oltvai +6 more
TL;DR: CCR is activated at an increased bacterial cell growth rate when it is required for optimal cell growth while intracellular macromolecular density is maintained within a narrow physiological range.
SMARTS: Reconstructing disease response networks from multiple individuals using time series gene expression data
Aaron Wise,Ziv Bar-Joseph +1 more
TL;DR: Scalable Models for the Analysis of Regulation from Time Series (SMARTS), a method integrating static and time series data from multiple individuals to reconstruct condition-specific response networks in an unsupervised way, was developed and applied to analyze human response to influenza and mouse brain development.