Aaron Monte
University of Wisconsin–La Crosse
39 Papers
111 Citations
Aaron Monte is an academic researcher from University of Wisconsin–La Crosse. The author has contributed to research in topics: Chemistry & Coupling reaction. The author has an hindex of 16, co-authored 39 publications. Previous affiliations of Aaron Monte include Purdue University & Wisconsin Alumni Research Foundation.
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Papers
Dihydrobenzofuran Analogues of Hallucinogens. 3.1 Models of 4-Substituted (2,5-Dimethoxyphenyl)alkylamine Derivatives with Rigidified Methoxy Groups2
Aaron Monte,Danuta Marona-Lewicka,Matthew A. Parker,David B. Wainscott,David L. Nelson,David E. Nichols +5 more
TL;DR: The results suggest that the dihydrofuran rings in these new analogues effectively model the active binding conformations of the methoxy groups of the parent compounds 1 and 2.
Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4-(methylenedioxy)amphetamine.
TL;DR: The results in the in vitro pharmacology studies indicate that selectivity for 5-HT versus catecholamine uptake carriers may be modulated by the position and orientation of ring oxygen atoms.
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Stereo- and regiospecific cu-catalyzed cross-coupling reaction of vinyl iodides and thiols: a very mild and general route for the synthesis of vinyl sulfides.
TL;DR: A mild and efficient method for the copper-catalyzed formation of vinylic carbon-sulfur bonds has been developed and the desired vinyl sulfides are obtained in good to excellent yields, with full retention of stereochemistry.
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Zebrafish Heart Failure Models for the Evaluation of Chemical Probes and Drugs
TL;DR: Two tractable heart failure models for drug discovery are established and three potential drugs have been identified that seem to attenuate heart failure by different mechanisms.
New classes of Gram-positive selective antibacterials: inhibitors of MRSA and surrogates of the causative agents of anthrax and tuberculosis.
M. Shahjahan Kabir,Kathleen C. Engelbrecht,Rebecca Polanowski,Sarah M. Krueger,Rachel Ignasiak,Marc Rott,William R. Schwan,Mary E. Stemper,Kurt D. Reed,David R. Sherman,James M. Cook,Aaron Monte +11 more
TL;DR: Preliminary structure–activity relationship studies indicated that both new classes of synthetic analogs, as well as the stilbenes, show promising activity against Gram-positive bacteria when at least one phenolic moiety is present, but not when absent.
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