Aaron C. Eifler
Northwestern University
16 Papers
52 Citations
Aaron C. Eifler is an academic researcher from Northwestern University. The author has contributed to research in topics: Medicine & Inferior vena cava. The author has an hindex of 8, co-authored 14 publications. Previous affiliations of Aaron C. Eifler include Stanford University.
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Papers
Nanoparticle therapeutics: FDA approval, clinical trials, regulatory pathways, and case study.
Aaron C. Eifler,C. Shad Thaxton +1 more
TL;DR: This chapter distils the drug development and approval process with an emphasis on special considerations for nanotherapeutics and a case study focused on a nanoparticle therapeutic, CALAA-01, currently in human clinical trials that embodies many of the potential benefits of nanoparticle therapeutics.
167
Image-guided local delivery strategies enhance therapeutic nanoparticle uptake in solid tumors.
Samdeep K. Mouli,Patrick D. Tyler,Joseph L. McDevitt,Aaron C. Eifler,Yang Guo,J. Nicolai,Robert J. Lewandowski,Weiguo Li,Daniel Procissi,Robert K. Ryu,Y. Andrew Wang,Riad Salem,Andrew C. Larson,Reed A. Omary +13 more
TL;DR: The design and testing of the innovative local delivery strategies are described, and it is demonstrated that local delivery techniques result in significantly increased intratumoral DOX-SPIO uptake, with limited off-target delivery in tumor-bearing animal models.
53
Optional or Permanent: Clinical Factors that Optimize Inferior Vena Cava Filter Utilization
Aaron C. Eifler,Robert J. Lewandowski,Ramona Gupta,J. Karp,Riad Salem,Jongmin Lee,Robert K. Ryu +6 more
TL;DR: Patient parameters can be used to quantitatively predict an optional IVC filter being kept permanent, and these findings can aid in optimization of prospective decision-making inIVC filter placement.
32
Patent
Methods and apparatus to deliver nanoparticles to tissue using electronanotherapy
Reed A. Omary,Andrew C. Larson,Samdeep K. Mouli,Aaron C. Eifler,Yang Guo +4 more
- 11 Oct 2011
TL;DR: In this paper, the delivery of nanoparticles to tissue using electro-nanotherapy or nanoablation is described. But the authors do not describe the systems, systems, and apparatus used to deliver nanoparticles.
22
Patent
Localized delivery of nanoparticles for therapeutic and diagnostic applications
Chad A. Mirkin,Reed A. Omary,C. Shad Thaxton,Aaron C. Eifler,Samdeep K. Mouli,Kaylin M. McMahon,Andrew C. Larson +6 more
- 04 Aug 2010
TL;DR: In this paper, the authors present compositions and methods of localized delivery of a functionalized nanoparticle (FPN) in order to improve the performance of the delivery of the nanoparticles.
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