Aadil Ali
University Health Network
25 Papers
16 Citations
Aadil Ali is an academic researcher from University Health Network. The author has contributed to research in topics: Lung transplantation & Transplantation. The author has an hindex of 5, co-authored 25 publications. Previous affiliations of Aadil Ali include Toronto General Hospital.
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Papers
Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion
M. Galasso,Jordan J. Feld,Y. Watanabe,M. Pipkin,C. Summers,Aadil Ali,R. Qaqish,Manyin Chen,R. Ribeiro,Khaled Ramadan,Layla Pires,Vanderlei Salvador Bagnato,Cristina Kurachi,Vera Cherepanov,Gray Moonen,A. Gazzalle,Thomas K. Waddell,Mingyao Liu,Shaf Keshavjee,Brian C. Wilson,Atul Humar,Marcelo Cypel +21 more
TL;DR: Physical viral clearance in combination with germicidal light-based therapies during normothermic ex-vivo Lung Perfusion (EVLP), a method for assessment and treatment of injured donor lungs, inactivates HCV virus in a short period of time and is shown to be safe and prevents HCV transmission in the pig model.
Static lung storage at 10°C maintains mitochondrial health and preserves donor organ function.
Aadil Ali,Aizhou Wang,R. Ribeiro,Erika L. Beroncal,Cristina Baciu,M. Galasso,B. Gomes,A. Mariscal,Olivia Hough,Edson Brambate,Etienne Abdelnour-Berchtold,V. Michaelsen,Yu Zhang,A. Gazzalle,Eddy Fan,Laurent Brochard,Laurent Brochard,Jonathan C. Yeung,Thomas K. Waddell,Mingyao Liu,Ana Cristina Andreazza,Shaf Keshavjee,Marcelo Cypel +22 more
TL;DR: In this article, cold static preservation on ice (~4°C) remains the clinical standard of donor organ preservation, however, mitochondrial injury develops during prolonged storage, which limits the extent of time th...
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Prediction of donor related lung injury in clinical lung transplantation using a validated ex vivo lung perfusion inflammation score.
A.T. Sage,Melissa Richard-Greenblatt,Kathleen Zhong,Xiao-Hui Bai,Matthew B. Snow,Monica Babits,Aadil Ali,Cristina Baciu,Jonathan C. Yeung,Mingyao Liu,Marcelo Cypel,Kevin C. Kain,Shaf Keshavjee,Shaf Keshavjee +13 more
TL;DR: In this article, the authors developed a protein-based assay that would provide a precision medicine approach to lung injury assessment during ex vivo lung perfusion (EVLP) during transplantation.
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Ex vivo lung perfusion for donor lung assessment and repair: a review of translational interspecies models
TL;DR: The review aims to guide investigators in choosing appropriate species model to suit their specific goals of study, and aid in translation of therapy to meet the growing needs of the patient population.
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Ex vivo treatment of cytomegalovirus in human donor lungs using a novel chemokine-based immunotoxin.
R. Ribeiro,Terrance Ku,Aizhou Wang,Layla Pires,Victor H Ferreira,V. Michaelsen,Aadil Ali,M. Galasso,S. Moshkelgosha,A. Gazzalle,Mads G. Jeppesen,Mette M. Rosenkilde,Mingyao Liu,Lianne G. Singer,Deepali Kumar,Shaf Keshavjee,John Sinclair,Thomas N Kledal,Atul Humar,Marcelo Cypel +19 more
TL;DR: In this article, an immunotoxin (F49A-FTP) was used to target and kill latent HCMV from donor lungs using ex-vivo lung perfusion (EVLP).
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