Aabha I. Sharma
Northwestern University
9 Papers
36 Citations
Aabha I. Sharma is an academic researcher from Northwestern University. The author has contributed to research in topics: Trypanosoma brucei & Palmitoylation. The author has an hindex of 7, co-authored 7 publications. Previous affiliations of Aabha I. Sharma include Wellesley College.
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Papers
Acylation in trypanosomatids: an essential process and potential drug target.
TL;DR: Protein acylation represents an attractive target for the development of new trypanosomatids drugs because of its importance for parasite growth, targeting and localization, and the intrinsic function of some proteins.
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Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts
Aabha I. Sharma,Cheryl L. Olson,João I. Mamede,Felipe Gazos-Lopes,Conrad L. Epting,Igor C. Almeida,David M. Engman,David M. Engman +7 more
TL;DR: Differences in the lipid rafts of an organism employing life cycle-specific sterols are illuminated and have implications for treatment.
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The phenotypic plasticity of developmental modules
Aabha I. Sharma,Aabha I. Sharma,Katherine O. Yanes,Luyang Jin,Luyang Jin,Sarah L. Garvey,Sartu M. Taha,Yuichiro Suzuki +7 more
TL;DR: It is proposed that when traits are regulated by distinct pre-patterning mechanisms, they can respond to the environment in a modular fashion, whereas when the environment impacts developmental regulators that are shared between different modules, phenotypic plasticity can manifest as a developmentally integrated system.
Sphingosine Kinase Regulates Microtubule Dynamics and Organelle Positioning Necessary for Proper G1/S Cell Cycle Transition in Trypanosoma brucei
TL;DR: The role of sphingosine kinase (SPHK) is investigated in the biology of the protozoan parasite Trypanosoma brucei, the agent of African sleeping sickness, and is found to be essential for normal growth and structure of the parasite, raising the possibility that it could be a good target for new chemotherapy for sleeping sickness.
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Emergency Department Visits and Hospitalizations for the Uninsured in Illinois Before and After Affordable Care Act Insurance Expansion.
TL;DR: Changes in emergency department (ED) visits and the proportion of patients with hospitalizations through the ED classified as Ambulatory Care Sensitive Hospitalization (ACSH) for the uninsured before and after Affordable Care Act (ACA) health insurance expansion in Illinois are described.
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