A. S. Reder
ODESSA
12 Papers
42 Citations
A. S. Reder is an academic researcher from ODESSA. The author has contributed to research in topics: Anticonvulsant & Flumazenil. The author has an hindex of 3, co-authored 12 publications.
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Papers
An effector analysis of the interaction of propoxazepam with antagonists of GABA and glycine receptors
TL;DR: Glycinergic components of the inhibition of strychnine-induced seizures by propoxazepam occur at doses that exceed the ED50 and seem to be an additional means of anti-seizure action.
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Evidence for the involvement of the GABA- ergic pathway in the anticonvulsant and antinociception activity of Propoxazepam in mice and rats
TL;DR: Propoxazepam in the tail-flick test and picrotoxin-induced convulsions showed significant analgesic and antiepileptic activity, and it can be suggested that the substance has no abuse-related actions.
Anti-inflammatory effects of propoxazepam on different models of inflammation
N. Ya. Golovenko,T. A. Kabanova,Sergei A. Andronati,O. I. Halimova,V. B. Larionov,A. S. Reder +5 more
TL;DR: It was established for the first time that the administration of Propoxazepam caused a significant anti-inflammatory activity when tested in different in vivo chemical experimental models of induced inflammation, i.e. carrageenan-, bradykininand formalin-induced inflammation tests.
Pharmacodynamics of Interaction between Propoxazepam and a GABA-Benzodiazepine Receptor-Ionofor Complex
TL;DR: It was found that the parameters of myoclonic components, as well as death time of the tested animals, characterize adequately an anticonvulsant action of propoxazepam of picrotoxin-induced seizures in mice.
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The effect of propoxazepam on development of thiosemicarbazide-induced GABA-deficient seizures in mice
M. Ya. Golovenko,A. S. Reder,V. B. Larionov,I. P. Valivodz,М. Я. Головенко,А. С. Редер,В. Б. Ларіонов,І. П. Валіводзь,Н. Я. Головенко,В. Б. Ларионов,И. П. Валиводзь +10 more
- 14 Jun 2017
TL;DR: The mean effective dose of propoxazepam as a protective effect on the model of thiosemicarbazide-induced seizures is 0.18 ± 0.10 mg/kg, indicating the increase in efficiency of inhibitory processes in the CNS.
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