A. Proctor
University College Dublin
8 Papers
46 Citations
A. Proctor is an academic researcher from University College Dublin. The author has contributed to research in topics: Chlamydophila abortus & Toxoplasma gondii. The author has an hindex of 6, co-authored 8 publications.
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Papers
Detection and quantification of Toxoplasma gondii in ovine maternal and foetal tissues from experimentally infected pregnant ewes using real-time PCR
Jorge Gutiérrez,J. O’Donovan,E. J. Williams,A. Proctor,C. Brady,P.X. Marques,Sheila Worrall,Jarlath E. Nally,Máire C. McElroy,H. F. Bassett,D. J. Sammin,David Buxton,Stephen W. Maley,Bryan Markey +13 more
TL;DR: Results indicate that the cotyledonary component of the foetal membranes is the sample of choice for the diagnosis of T. gondii by rt-PCR, followed byfoetal lung and brain.
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Monitoring clinical outcomes, pathological changes and shedding of Chlamydophila abortus following experimental challenge of periparturient ewes utilizing the natural route of infection
Jorge Gutiérrez,E. J. Williams,J. O’Donovan,C. Brady,A. Proctor,P.X. Marques,Sheila Worrall,Jarlath E. Nally,Máire C. McElroy,H. F. Bassett,D. J. Sammin,Bryan Markey +11 more
TL;DR: Results indicate that C. abortus can be detected in a large proportion of animals during the first pregnancy after oral infection, however, this proportion is reduced at the subsequent breeding season, confirming the occurrence of a chronic low level persistent infection in post-abortion/lambing ewes.
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Distribution of Lesions in Fetal Brains Following Experimental Infection of Pregnant Sheep With Toxoplasma gondii
J. O’Donovan,A. Proctor,Jorge Gutiérrez,S. Worrell,Jarlath E. Nally,P.X. Marques,C. Brady,Máire C. McElroy,D. J. Sammin,David Buxton,Stephen W. Maley,H. F. Bassett,Bryan Markey +12 more
TL;DR: Histopathologic examination of transverse sections taken at 13 levels in the fetal brains revealed the presence of toxoplasmosis-related lesions in all 6 brains, but lesions were not randomly distributed.
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Identification of Immunologically Relevant Proteins of Chlamydophila abortus Using Sera from Experimentally Infected Pregnant Ewes
P.X. Marques,Puneet Souda,J. O’Donovan,Jorge Gutiérrez,E. J. Gutierrez,Sheila Worrall,Máire C. McElroy,A. Proctor,C. Brady,D. J. Sammin,H. F. Basset,Julian P. Whitelegge,B. E. Markey,Jarlath E. Nally +13 more
TL;DR: Serum samples collected from experimentally infected pregnant ewes reacted specifically with several antigens of EB as determined by one-dimensional (1-D) and 2-D gel electrophoresis; reactiveAntigens identified by mass spectrometry included the major outer membrane protein (MOMP), polymorphic outer membraneprotein (POMP, and macrophage infectivity potentiator (MIP) lipoprotein).
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Detection of Toxoplasma gondii antigens reactive with antibodies from serum, amniotic, and allantoic fluids from experimentally infected pregnant ewes.
P.X. Marques,J. O’ Donovan,E. J. Williams,Jorge Gutiérrez,Jorge Gutiérrez,Sheila Worrall,Máire C. McElroy,A. Proctor,C. Brady,D. J. Sammin,H. F. Bassett,David Buxton,Stephen W. Maley,Bryan Markey,Jarlath E. Nally +14 more
TL;DR: Results suggest a maternal source of immunoglobulin in the allantoic fluid and a foetal source of immune source in the amniotic fluid early in infection but that both sources may contribute immunoglobeulin to both fluids at a later stage.
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