13 Papers
296 Citations
A Minty is an academic researcher from Mario Negri Institute for Pharmacological Research. The author has contributed to research in topics: Interleukin 13 & Cytokine. The author has an hindex of 12, co-authored 13 publications.
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Papers
Function of the interleukin-2 (IL-2) receptor gamma-chain in biologic responses of X-linked severe combined immunodeficient B cells to IL-2, IL-4, IL-13, and IL-15.
DJ Matthews,P A Clark,J. Herbert,Gareth Morgan,Richard J. Armitage,Christine Kinnon,A Minty,KH Grabstein,D. Caput,P Ferrara +9 more
TL;DR: B cells from two X-SCID patients with characterized gamma c-chain gene mutations do not respond to IL-2 or IL-15, but respond as well or better than normal B cells to both IL-4 and IL-13 in assays for B-cell activation, proliferation, and IgE secretion.
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Regulation of endothelial and mesothelial cell function by interleukin-13: selective induction of vascular cell adhesion molecule-1 and amplification of interleukin-6 production.
Marina Sironi,Francesca L. Sciacca,Cristian Matteucci,M. Conni,Annunciata Vecchi,Sergio Bernasconi,A Minty,D. Caput,P Ferrara,Francesco Colotta +9 more
TL;DR: IL-13 elicits a spectrum of responses in vascular endothelium remarkably similar to that of IL-4 and IL-10, which may play an important role in the induction and expression of Th2-dependent responses.
123
•Journal Article
IL-13 supports differentiation of dendritic cells from circulating precursors in concert with GM-CSF.
Lorenzo Piemonti,Sergio Bernasconi,Walter Luini,Zlatko Trobonjača,A Minty,Paola Allavena,A. Mantovani +6 more
TL;DR: It is concluded that IL-13 is as effective as IL-4, combined with GM-CSF in sustaining DC differentiation from PBMC and that activation of the common gamma chain-driven transduction pathways is dispensable for DC differentiation and function.
115
Interleukin-13 induces expression and release of interleukin-1 decoy receptor in human polymorphonuclear cells.
Francesco Colotta,Fabio Re,Marta Muzio,Nadia Polentarutti,A Minty,D. Caput,P Ferrara,Alberto Mantovani +7 more
TL;DR: Results show that PMN is an important target for IL-13 and that induction of expression and release of the IL-1 decoy R, in concert with inhibition of cytokine synthesis, may represent an important mechanism by whichIL-13 blocks IL- 1, a central mediator of inflammatory reactions.
85
•Journal Article
Molecular cloning of the MCP-3 chemokine gene and regulation of its expression.
A Minty,Pascale Chalon,Jean-Claude Guillemot,Mourad Kaghad,P. Liauzun,Magazin M,Brigitte Miloux,C. Minty,P. Ramond,Natalio Vita +9 more
TL;DR: In this paper, a cDNA (NC28) transcribed from a mRNA which is transiently induced in U937 promonocytic cells by PMA and super-induced by cycloheximide.
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