A. Merrill Knapp
Stanford University
5 Papers
85 Citations
A. Merrill Knapp is an academic researcher from Stanford University. The author has contributed to research in topics: Keratinocyte & Epidermis. The author has an hindex of 5, co-authored 5 publications.
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Papers
Changes in keratinocyte maturation during wound healing.
TL;DR: Keratinocytes in culture and in psoriatic skin express maturation markers very similar to those seen following epidermal injury, suggesting participation of both regenerative and normal maturation pathways together rather than all-or-nothing switching of one pathway to the other.
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Transforming growth factor-beta 1 localization in normal and psoriatic epidermal keratinocytes in situ.
TL;DR: The conformation or structure of TGFβ1 and its localization vary in keratinocytes with distinct differentiation phenotypes suggesting that TGF β1 is a potential modulator of keratinocyte differentiation in vivo.
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Evidence for an Alternative Pathway of Keratinocyte Maturation in Psoriasis from an Antigen Found in Psoriatic but Not Normal Epidermis
TL;DR: The psi-3 antigen is interpreted as a new keratinocyte product expressed in psoriasis, culture, wound healing, and certain other pathologic skin conditions and supports the hypothesis that psoriatic keratinocytes are following an alternative pathway.
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The Binding of Helix pomatia and Ulex europeus Agglutinins to Normal and Psoriatic Skin
TL;DR: The result indicates the production of a component early in the maturation pathway which has no counterpart in normal skin which is largely sensitive to chloroform/methanol extraction, and thus presumably is glycolipid in nature.
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Histologic Distribution of Staining by a Monoclonal Antibody (ψ-3) in Psoriasis and Occurrence of ψ-3 Antigen in Other Cutaneous Diseases
TL;DR: The occurrence of psi-3 antigen cannot be correlated with any histologic feature of psoriasis such as acanthosis, loss of the granular layer, or hyperproliferation, and appears to be a unique keratinocyte constituent which is expressed in certain pathologic conditions and which is not detected by any other histologic or immunophenotyping method.
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