A. M. Flack
Trinity College, Dublin
2 Papers
33 Citations
A. M. Flack is an academic researcher from Trinity College, Dublin. The author has contributed to research in topics: Virus & Semliki Forest virus. The author has an hindex of 2, co-authored 2 publications.
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Papers
Teratogenicity of the Semliki Forest virus mutant ts22 for the foetal mouse: induction of skeletal and skin defects.
M. J. E. M. F. Mabruk,A. M. Flack,Gwendoline M. Glasgow,J. M. B. Smyth,J. C. Folan,J. G. Bannigan,O'Sullivan Ma,Brian J. Sheahan,Gregory J. Atkins +8 more
TL;DR: It is proposed that the skeletal and skin defects induced in mouse foetuses by ts22 infection result from the tropism of the virus for mesenchymal cells involved in the development of such tissue.
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Effect of infection with the ts22 mutant of Semliki Forest virus on development of the central nervous system in the fetal mouse.
M. J. E. M. F. Mabruk,G M Glasglow,A. M. Flack,J. C. Folan,J. G. Bannigan,J. M. B. Smyth,O'Sullivan Ma,Brian J. Sheahan,Gregory J. Atkins +8 more
TL;DR: It was shown that the skin and musculoskeletal systems of fetuses from mothers infected with ts22 were often heavily infected but the central nervous systems were not labeled before day 17 of pregnancy, which appeared to be indirect and caused by virus infection of mesenchymal cells surrounding the developing neural tube.