A. Lu
9 Papers
A. Lu is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 5 publications.
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Papers
The metastasis suppressor, NDRG1, inhibits “stemness” of colorectal cancer via down-regulation of nuclear β-catenin and CD44
Xiongzhi Wangpu,Xiao Yang,Jingkun Zhao,Jiaoyang Lu,Shaopei Guan,Jun Lu,Zaklina Kovacevic,Wensheng Liu,Lan Mi,Runsen Jin,Jing Sun,Fei Yue,Junjun Ma,A. Lu,Des R. Richardson,Lishun Wang,Minhua Zheng +16 more
TL;DR: It is demonstrated that CRC cells with silenced NDRG1 showed more tumorigenic ability and stem cell-like properties, such as: colony and sphere formation, chemoresistance, cell invasion, high expression of CD44, and tumorigenicity in vivo.
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DNA repair mechanisms that promote insertion-deletion events during immunoglobulin gene diversification
Qian Hao,Chuanzong Zhan,Chaoyang Lian,Simin Luo,Wenyi Cao,Binbin Wang,Xia Xie,Xiaofei Ye,Tuantuan Gui,Claudia Voena,Chiara Pighi,Yanyan Wang,Ying Tian,Xin Wang,Pengfei Dai,Yanni Cai,Xiaojing Liu,Shengqun Ouyang,Shi Yu Sun,Qianwen Hu,Jun Lu,Youqiong Ye,Jingkun Zhao,A. Lu,Jian Wang,Chuanxin Huang,Bing Su,Fei-Long Meng,Roberto Chiarle,Qiang Pan-Hammarström,Leng-Siew Yeap +30 more
TL;DR: Hao et al. as discussed by the authors carried out ultra-deep profiling of indels and systematically dissected the underlying mechanisms using passenger-immunoglobulin mouse models, revealing the mechanisms that generate beneficial and deleterious indels during the process of antibody somatic hypermutation and has implications in understanding the detrimental genomic alterations in various conditions, including tumorigenesis.
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Intracorporeal versus extracorporeal anastomosis in laparoscopic right colectomy: a retrospective study
F. Chen,Zeping Lv,Wenqing Feng,Zhuoqing Xu,Yiming Miao,Zifeng Xu,Yuchen Zhang,Han Gao,MinHua Zheng,Yaping Zong,Jingkun Zhao,A. Lu +11 more
TL;DR: In this article , the authors investigated the potential advantages in postoperative recovery and safety of IIA in laparoscopic right colectomy (LRC) and found that IIA is associated with faster GI function recovery and less postoperative pain and may be more favorable for obese patients.
Pathological and perioperative outcomes of extracorporeal versus intracorporeal anastomosis in laparoscopic transverse colon cancer resection: retrospective multicentre study
H.-D. Zhong,Zhenghao Cai,Junyang Lu,Yingchi Yang,Qing Xu,Nan Wang,Lifang He,Xiyue Hu,Abe Fingerhut,Minhua Zheng,A. Lu,Zheng Liu,Yi-Qin Xiao,Bo Feng +13 more
TL;DR: Wang et al. as mentioned in this paper compared the pathological and perioperative outcomes of extracorporeal versus intracorporeal anastomosis after laparoscopic transverse colon cancer resection.
High ligation versus low ligation of the inferior mesenteric artery in laparoscopic rectal cancer surgery: a retrospective study on surgical and long-term outcome
Wenqing Feng,Yiming Miao,Wenchang Li,Zifeng Xu,Fangqian Chen,Zeping Lv,Wangyi Liu,Minhua Zheng,Jingkun Zhao,Yaping Zong,A. Lu +10 more
TL;DR: Low ligation of the IMA which reserved LCA with vascular root lymph node dissection in laparoscopic low anterior resection for rectal cancer surgery may help protect the blood supply of the anastomosis, and will not increase postoperative complications while enhance recovery, without compromising radical excision and long-term prognosis.