A. Konur
University of Regensburg
7 Papers
60 Citations
A. Konur is an academic researcher from University of Regensburg. The author has contributed to research in topics: Autocrine signalling & Antigen. The author has an hindex of 6, co-authored 7 publications.
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Papers
Interferon (IFN)-gamma is a main mediator of keratinocyte (HaCaT) apoptosis and contributes to autocrine IFN-gamma and tumour necrosis factor-alpha production.
TL;DR: The apoptosis of keratinocytes or intestinal epithelial cells is an important pathophysiological mechanism of organ damage during acute graft‐versus‐host disease and should be considered a priority for further research.
58
Three-dimensional co-culture of human monocytes and macrophages with tumor cells: analysis of macrophage differentiation and activation
TL;DR: A 3‐dimensional interaction with tumor cells in vitro results in significant changes in the phenotype and function of the spheroid‐associated MO and MAC, indicating a disturbed MO to MAC maturation within tumor spheroids.
56
Naive monocytes can trigger transendothelial migration of peripheral blood cells through the induction of endothelial tumour necrosis factor-alpha.
TL;DR: A potentially new mechanism by which unstimulated human monocytes activate endothelial cells (EC) through the secondary induction of endothelial tumour necrosis factor alpha (TNF‐α) is described, which may have an impact for transplantational settings that donor monocytes may trigger an inflammatory response in the absence of further activation signals.
7
Monocyte-Derived Cells in Adoptive Immunotherapy of Cancer: Facts and Perspectives
Stefan W. Krause,B. Hennemann,A. Konur,Marina Kreutz,Reinhard Andreesen +4 more
- 01 Jan 1997
TL;DR: The immune system is able to cope with infectious and malignant disease by a complicated network that includes innate and adaptive mechanisms as discussed by the authors, and cells of the mononuclear phagocyte system play a prominent role in innate immunity.
The detection of apoptosis in a human in vitro skin explant assay for graft versus host reactions
M. Jarvis,Ute Schulz,Anne M. Dickinson,Lisbet Sviland,Graham Jackson,A. Konur,X N Wang,Ilona Hromadnikova,Kolb Hj,Günther Eissner,Ernst Holler +10 more
TL;DR: The detection of apoptosis correlated with degree of GVHR using an in vitro assay and a higher degree of apoptotic cells tended to correlate with more severe GVHD.