A Hjalmarson
University of Gothenburg
11 Papers
156 Citations
A Hjalmarson is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Receptor & Epitope. The author has an hindex of 11, co-authored 11 publications.
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Papers
Autoimmunity in idiopathic dilated cardiomyopathy. Characterization of antibodies against the beta 1-adrenoceptor with positive chronotropic effect.
TL;DR: The second extracellular loop of the beta 1-adrenoceptor is a specific target for antibodies with stimulatory activity detected in patients with idiopathic DCM and the antibodies have a positive chronotropic effect on isolated rat heart myocytes.
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Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy.
Yvonne Magnusson,Stefano Marullo,S Hoyer,Finn Waagstein,Björn Andersson,A Vahlne,Jean-Gérard Guillet,Arthur Donny Strosberg,A Hjalmarson,Johan Hoebeke +9 more
TL;DR: It is concluded that a subgroup of patients with idiopathic dilated cardiomyopathy have in their sera autoantibodies specifically directed against the second extracellular loop of the beta 1-adrenergic receptor.
•Journal Article
Antigenic analysis of the second extra-cellular loop of the human beta-adrenergic receptors.
Yvonne Magnusson,S Hoyer,R Lengagne,M P Chapot,Jean-Gerard Guillet,A Hjalmarson,Arthur Donny Strosberg,J. Hoebeke +7 more
TL;DR: The results suggest that the second extracellular loop postulated in the structure of the human beta-adrenergic receptor contains the T and B cell epitopes necessary for induction of an immune response.
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•Journal Article
Myocardial infarction. Effects of beta-blockade.
A Hjalmarson,G Olsson +1 more
TL;DR: Report from extended follow-ups after termination of initial double-blind beta-blocker studies in postinfarction patients indicate that withdrawal of the active treatment may increase mortality after cessation of treatment, despite measures having been taken to avoid so-called acute withdrawal phenomena.
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Characterization of anti-peptide antibodies directed against an extracellular immunogenic epitope on the human α1-adrenergic receptor
TL;DR: The results constitute the first immunochemical evidence of the presence of both the A and B subtypes of the α1‐adrenergic receptor in the heart and confirm that the second extracellular loop of theα1‐ adrenergic receptors is an immunologically and functionally important domain.
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