A. Hatton
University of Paris
6 Papers
33 Citations
A. Hatton is an academic researcher from University of Paris. The author has contributed to research in topics: RNA splicing & In vivo. The author has an hindex of 2, co-authored 6 publications. Previous affiliations of A. Hatton include French Institute of Health and Medical Research.
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Papers
Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10 kb C-to-T splicing mutation
Yifat S. Oren,Michal Irony-Tur Sinai,A. Golec,Ofra Barchad-Avitzur,Venkateshwar Mutyam,Yao Li,Jeong S. Hong,Efrat Ozeri-Galai,A. Hatton,Chen Leibson,Liran Carmel,Joel Reiter,Eric J. Sorscher,Steve D. Wilton,Steve D. Wilton,Eitan Kerem,Steven M. Rowe,Isabelle Sermet-Gaudelus,Batsheva Kerem +18 more
TL;DR: In this paper, the authors developed an ASO-based splicing modulation therapy for CF patients carrying the 3849+10-kb C-to-T splicing mutation in the CFTR gene.
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New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation.
Sara Bitam,Ahmad Elbahnsi,Geordie Creste,Iwona Pranke,Benoit Chevalier,Farouk Berhal,Brice Hoffmann,Nathalie Servel,Nesrine Baatalah,Danielle Tondelier,A. Hatton,Christelle Moquereau,Mélanie Faria Da Cunha,Alexandra Pastor,Agathe Lepissier,Alexandre Hinzpeter,Jean-Paul Mornon,Guillaume Prestat,Aleksander Edelman,Isabelle Callebaut,Christine Gravier-Pelletier,Isabelle Sermet-Gaudelus,Isabelle Sermet-Gaudelus +22 more
TL;DR: In this article, the authors investigated the effect of C407 and derivatives on CFTR protein and showed that C407 alone or in combination with the F508del-CFTR corrector VX-809, increased CFTR activity in cell lines but not in primary respiratory cells carrying the p.Phe508del (F508del) mutation.
Author Correction: New insights into structure and function of bis-phosphinic acid derivatives and implications for CFTR modulation.
Sara Bitam,Ahmad Elbahnsi,Geordie Creste,Iwona Pranke,Benoit Chevalier,Farouk Berhal,Brice Hoffmann,Nathalie Servel,Nesrine Baatalah,Danielle Tondelier,A. Hatton,Christelle Moquereau,Mélanie Faria Da Cunha,Alexandra Pastor,Agathe Lepissier,Alexandre Hinzpeter,Jean-Paul Mornon,Guillaume Prestat,Aleksander Edelman,Isabelle Callebaut,Christine Gravier‑Pelletier,Isabelle Sermet‑Gaudelus,Isabelle Sermet‑Gaudelus +22 more
Antisense oligonucleotide-based drug development for Cystic Fibrosis patients carrying the 3849+10kb C-to-T splicing mutation
Yifat S. Oren,M. Irony-Tur Sinai,A. Golec,O. Barchad-Avitzur,Venkateshwar Mutyam,Yuanyuan Li,Jeong S. Hong,Efrat Ozeri-Galai,A. Hatton,Joel Reiter,Eric J. Sorscher,Steve D. Wilton,Eitan Kerem,Steven M. Rowe,Isabelle Sermet-Gaudelus,Batsheva Kerem +15 more
TL;DR: In this article, an ASO-based splicing modulation therapy for CF patients carrying the 3849+10kb C-to-T splicing mutation in the CFTR gene was developed.
25 Unsolved severe chronic rhinosinusitis elucidated by extensive CFTR genotyping
F. Degrugillier,S. Simon,N. Remus,C. Mekki,L. Bassinet,X. Decrouy,Isabelle Sermet-Gaudelus,A. Hatton,Brice Hoffmann,Alexandre Hinzpeter,Isabelle Callebaut,Pascale Fanen,Virginie Prulière-Escabasse +12 more
TL;DR: This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.