A. Gaafar
University of Copenhagen
18 Papers
402 Citations
A. Gaafar is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Cutaneous leishmaniasis & Leishmania major. The author has an hindex of 14, co-authored 14 publications. Previous affiliations of A. Gaafar include University of Khartoum & Copenhagen University Hospital.
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Papers
T-cell response in human leishmaniasis.
Arsalan Kharazmi,K. Kemp,A. Ismail,S. Gasim,A. Gaafar,Jørgen A. L. Kurtzhals,A.M. El Hassan,Thor G. Theander,Michael Kemp +8 more
TL;DR: Evidence is provided for the existence of a Th1/Th2 dichotomy in the T-cell response to Leishmania antigens in human leishmaniasis and the data suggest that the pattern of IL-4 and IFN-gamma response is polarised in these patients.
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Dichotomy of the human T cell response to Leishmania antigens. I. Th1-like response to Leishmania major promastigote antigens in individuals recovered from cutaneous leishmaniasis.
Michael Kemp,A. S. Hey,Jørgen A. L. Kurtzhals,C. B. V. Ch Ristensen,A. Gaafar,A. Gaafar,Mustafa D. Mustafa,A. A. Y. Kordofani,A. Ismail,Arsalan Kharazmi,Thor G. Theander +10 more
TL;DR: The data show that the T cell response to Leishmania antigens in humans who have had uncomplicated CL or subclinical L. major infection is an IFN‐γ‐producing Th1‐like response.
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Evaluation of the polymerase chain reaction in the diagnosis of cutaneous leishmaniasis due to Leishmania major: a comparison with direct microscopy of smears and sections from lesions.
K. Andresen,A. Gaafar,A. Gaafar,Ahmed M. Elhassan,A. Ismail,M. Dafalla,Thor G. Theander,A. Kharazmi +7 more
TL;DR: The PCR should be considered as a valuable and sensitive diagnostic tool in the diagnosis of cutaneous leishmaniasis; it has the added advantage of identification of the species of Leishmania causing the lesion.
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Characterization of the local and systemic immune responses in patients with cutaneous leishmaniasis due to Leishmania major.
TL;DR: In this article, skin biopsies and peripheral blood samples were obtained from patients with cutaneous leishmaniasis caused by leishmania major, and they were obtained at diagnosis and during healing when the lesions had regressed to half the original size.
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Dichotomy of the T cell response to Leishmania antigens in patients suffering from cutaneous leishmaniasis; absence or scarcity of Th1 activity is associated with severe infections
A. Gaafar,Arsalan Kharazmi,A. Ismail,Michael Kemp,A. S. Hey,Claus Christensen,M. Dafalla,A. Y. El Kadaro,A.M. El Hassan,Thor G. Theander +9 more
TL;DR: The T cell response was studied in 25 patients suffering from cutaneous leishmaniasis caused by Leishmania major with severe and mild disease manifestations.
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