A. Drzezga
Technische Universität München
16 Papers
251 Citations
A. Drzezga is an academic researcher from Technische Universität München. The author has contributed to research in topics: Dementia & Frontotemporal dementia. The author has an hindex of 11, co-authored 16 publications.
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Papers
Cerebral metabolic patterns at early stages of frontotemporal dementia and semantic dementia. A PET study.
TL;DR: In the clinical syndromes of FTD and SD two distinct patterns of cerebral metabolism were identified: FTD was associated with frontal hypometabolism, whereas in SD cerebral glucose metabolism was exclusively reduced in the temporal lobes.
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Decline of cerebral glucose metabolism in frontotemporal dementia: a longitudinal 18F-FDG-PET-study.
Janine Diehl-Schmid,Timo Grimmer,A. Drzezga,Susanne Bornschein,Matthias Riemenschneider,Hans Förstl,Markus Schwaiger,Alexander Kurz +7 more
TL;DR: In early stages of FTD the neurodegenerative process is limited to the frontal lobes, and during the progression of the disease the pathological changes pass over the lobar borders and spread into the parietal and temporal cortices.
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Regular papers Resting metabolic connectivity in prodromal Alzheimer's disease. A European Alzheimer Disease Consortium (EADC) project
Silvia Morbelli,A. Drzezga,Robert Perneczky,Giovanni B. Frisoni,Anna Caroli,Rik Ossenkoppele,Eric Guedj,Gianmario Sambuceti,Marco Pagani,Eric Salmon,Flavio Nobili +10 more
- 01 Jan 2012
TL;DR: In this paper, the authors explored resting-state metabolic connectivity in prodromal Alzheimer's disease (pAD) patients and in healthy controls (CTR) through a voxel-wise interregional correlation analysis of 18F-fluorodeoxyglucose-positron emission tomography (PET) by means of statistical parametric mapping.
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Resting metabolic connectivity in prodromal Alzheimer's disease. A European Alzheimer Disease Consortium (EADC) project
Silvia Morbelli,A. Drzezga,Robert Perneczky,Giovanni B. Frisoni,Anna Caroli,Bart N.M. van Berckel,Rik Ossenkoppele,Eric Guedj,Mira Didic,Andrea Brugnolo,Gianmario Sambuceti,Marco Pagani,Eric Salmon,Flavio Nobili +13 more
TL;DR: The reduced metabolic connections both in hypometabolic and nonhypometabolic areas in pAD patients suggest that metabolic disconnection (reflecting early diaschisis) may antedate remote hypometabolism (early sign of synaptic degeneration).
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Region-specific decline of cerebral glucose metabolism in patients with frontotemporal dementia: a prospective 18F-FDG-PET study.
TL;DR: Compared with normal controls, FTD patients showed significant metabolic deficits primarily in frontal cortical areas, but also in the caudate nuclei and the thalami.
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