A Boneu
9 Papers
32 Citations
A Boneu is an academic researcher. The author has contributed to research in topics: Penetrance & Multiple endocrine neoplasia type 2. The author has an hindex of 8, co-authored 9 publications.
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Papers
Prognostic factors for survival and for biochemical cure in medullary thyroid carcinoma: results in 899 patients
E. Modigliani,Régis Cohen,José-Marie Campos,Bernard Conte-Devolx,Béatrice Maes,A Boneu,Martin Schlumberger,J. C. Bigorgne,Philippe Dumontier,Laurence Leclerc,Bernard Corcuff,Isabelle Guilhem +11 more
TL;DR: Prognostic factors of sporadic or inherited medullary thyroid carcinoma (MTC) are still controversial and have been assessed in old and small series.
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Multiple Endocrine Neoplasia Type 2: Management of Patients and Subjects at Risk
Bernard Conte-Devolx,I Schuffenecker,P Niccoli,Bart Maes,A Boneu,N Barbot,JB Corcuff,Arnaud Murat,Jf Henry,E. Modigliani +9 more
TL;DR: This step of biological investigations enables the earliest possible treatment of any endocrine lesion detected before it is expressed clinically, thus improving the prognosis of MEN-2.
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•Journal Article
Early therapeutic management of patients genetically predisposed to medullary thyroid cancer
Arnaud Murat,E. Modigliani,Bernard Conte-Devolx,Rohmer,L Leclerc,I. Guilhem,J. C. Bigorgne,A Boneu,Bart Maes,Olivier Chabre,P Niccoli,I Schuffenecker,S Giraud +12 more
TL;DR: Thyroidectomy should be performed at a very young age in RET mutation carriers, regardless of the plasma CT values, according to the preoperative calcitonin response to pentagastlin.
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Risk and penetrance of primary hyperparathyroidism in multiple endocrine neoplasia type 2A families with mutations at codon 634 of the RET proto-oncogene. Groupe D'etude des Tumeurs à Calcitonine.
I Schuffenecker,Marie Virally-Monod,Richard M. Brohet,David E. Goldgar,Bernard Conte-Devolx,L Leclerc,Olivier Chabre,A Boneu,J. Caron,C. Houdent,E. Modigliani,Vincent Rohmer,M. Schlumberger,Charis Eng,Pierre Jean Guillausseau,Gilbert M. Lenoir +15 more
TL;DR: It is demonstrated that HPT could be an early component of the disease and provided the first estimate of age-specific and mutation-specific HPT penetrance in individuals with mutations of codon 634 of the RET proto-oncogene.
Risk and Penetrance of Primary Hyperparathyroidism in Multiple Endocrine Neoplasia Type 2A Families with Mutations at Codon 634 of the RET Proto-Oncogene
I Schuffenecker,Marie Virally-Monod,Richard M. Brohet,David E. Goldgar,Bernard Conte-Devolx,Laurence Leclerc,Olivier Chabre,A Boneu,Jean Caron,C. Houdent,E. Modigliani,Vincent Rohmer,Martin Schlumberger,Charis Eng,Pierre Jean Guillausseau,Gilbert M. Lenoir +15 more
TL;DR: It is demonstrated that HPT could be an early component of the disease and provided the first estimate of age-specific and mutation-specific HPT penetrance in individuals with mutations of codon 634 of the RET proto-oncogene.