A. Antonelli
Sapienza University of Rome
20 Papers
163 Citations
A. Antonelli is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Ataxia-telangiectasia & Telomere. The author has an hindex of 12, co-authored 20 publications.
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Papers
Variant of ataxia-telangiectasia with low-level radiosensitivity
Massimo Fiorilli,A. Antonelli,Giandomenico Russo,Marco Crescenzi,Maurizio Carbonari,P. Petrinelli +5 more
TL;DR: Cells from several patients clinically diagnosed as having ataxia-telangiectasia showed normal inhibition of DNA synthesis and levels of induced chromosomal aberrations intermediate between normal and AT cells, appearing to define one distinct subset of AT.
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TCL1 oncogene activation in preleukemic T cells from a case of ataxia-telangiectasia
Maria Grazia Narducci,Laura Virgilio,Masaharu Isobe,Antonella Stoppacciaro,Raffaella Elli,Massimo Fiorilli,Maurizio Carbonari,A. Antonelli,Luciana Chessa,Carlo M. Croce,Giandomenico Russo +10 more
TL;DR: Data indicate that TCL1 is activated in preleukemic clonal cells as a consequence of chromosome translocation involving sequences from the TCR locus at 14q11.1, the first event in the initiation of malignancy in these types of leukemias.
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Inhibition of c-Myc Oncoprotein Limits the Growth of Human Melanoma Cells by Inducing Cellular Crisis
TL;DR: It is shown that inhibition of c-Myc causes a proliferative arrest of M14 melanoma cells through cellular crisis, evident by the increase in size, multiple nuclei, vacuolated cytoplasm, induction of senescence-associated β-galactosidase activity and massive apoptosis.
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Telomere dysfunction increases cisplatin and ecteinascidin-743 sensitivity of melanoma cells.
Annamaria Biroccio,Chiara Gabellini,Sarah Amodei,Barbara Benassi,Donatella Del Bufalo,Raffaella Elli,A. Antonelli,Maurizio D'Incalci,Gabriella Zupi +8 more
TL;DR: Reconstitution of telomerase activity by exogenous hTERT expression improved telomere function and reduced the sensitivity to CDDP and ET-743 without affecting LND susceptibility.
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Establishment of a new Epstein-Barr virus-immortalized cell line from chronic lymphocytic leukemia with trisomy of chromosome 12 that produces monoclonal IgM against a sheep RBC antigen.
Marco Crescenzi,M Napolitano,Maurizio Carbonari,A. Antonelli,P. Petrinelli,Carlo Gaetano,Massimo Fiorilli +6 more
TL;DR: To the authors' knowledge, this is the first EBV-immortalized cell line from B-CLL cells of known SRBC specificity and the third reported CLL cell line carrying trisomy of chromosome 12.
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