Ureteral stents are commonly used in clinical treatment of ureteral diseases. There were a series of complications, such as biofilms and crusts caused by bacteria after surgery. Therefore, biodegradable with bacteriostatic ureteral scaffolds would be the potential to solve above mentioned problems. In this study, nanosilver (AgNP) was added to the polylactic‐co‐glycolic acid (PLGA) and polycaprolactone (PCL) to prepare biodegradable antibacterial ureteral scaffold samples by 3D printing. The biocompatibility, antibacterial properties, degradability, and mechanical properties of samples were observed. The samples were under a strong inhibitory effect on both Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), and the higher the concentration of AgNP, the stronger the antibacterial effect. When the concentration of AgNP was 10%, the antibacterial effect was up to 100%. AgNP was released continually with the degradation of samples, which can achieve a continuous antibacterial effect. The breaking strength of the samples without and with AgNP were 6.08 ± 1.16 MPa and 26.02 ± 2.00 MPa. The mechanical properties of samples with AgNP were higher than those without AgNP. It provides a potential way to design ureteral scaffolds based on biodegradable polymers with AgNP in the clinic.

Degradation behavior of polylactic‐co‐glycolic acid and polycaprolactone with nanosilver scaffolds

Obstetric Fistula

Ureteral stents are commonly used in urological practices but are frequently associated with patient discomfort, encrustation and stent-related infection. And a second procedure is needed to remove the stent. New biomaterials and designs have been attempted to solve these problems. The development of biodegradable ureteral stent shows promising prospects in future clinical applications. This article reviews the biomaterials and preparation methods commonly used in the present study of biodegradable ureteral stents. To date, none of the technological developments has lead to the 'ideal' biodegradable ureteral stent, but much progress has been made in the stent design by improving the physical characteristics and biocompatibility of the biomaterials. The controllability of degradation, the biggest problem faced currently, still needs to be further improved. In the future, the nanotechnology and chemical modification of biomaterials may be able to further optimize the properties of degradation.

Prospects for the research and application of biodegradable ureteral stents: from bench to bedside.

The purpose of this study is to describe a simple, non-expensive, accessible and effective technique of ureterovaginal fistula diagnosis, and to assess the results of surgical management in a resource-constrained hospital. During a campaign of obstetric fistulas repair, we diagnosed ureterovaginal fistulas by vaginal exam with the blue methylene test associated to abdominal ultrasonography, two simple and non-expensive explorations which permitted to identify ureterovaginal fistula and to do differential diagnosis with vesicovaginal fistula. The management was surgery, by ureterovesical reimplantation. Four ureterovaginal fistulas have been diagnosed in 32 women presented with obstetrical fistula. The mean age of those fistulas was 4.85 years; it was located on the left ureter in three cases, on the right in one case. The ureteral lesion was consecutive to a caesarean section in all patients and sited on the pelvic segment of ureter. In three patients, diagnosis was performed by the negativity of the blue test and unilateral dilation of ureter and kidney while the discovery was done during the treatment of vesicovaginal and rectovaginal fistulas associated in the last patient. After effects of surgery were simple, characterized by disappearance of urine leakage and dilation of ureter kidney. In resources-constrained context, techniques such as blue test and ultrasonography are enough to perform diagnosis of ureterovaginal fistula. Ureterovesical reimplantation is an effective therapeutic method for diagnosing ureterovaginal fistula.

[Ureterovaginal fistula after caesarean: Diagnosis and management in a resource-constrained hospital in Togo].

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[Ureterovaginal fistula after caesarean: Diagnosis and management in a resource-constrained hospital in Togo].